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56 Dissolution Technologies | NOVEMBER 2014UV Spectrophotometric Method for Determination of the Dissolution Profile of RivaroxabanMustafa elebier1, Mustafa Sinan Kaynak2,Sacide Alt n z1,*, and Selma Sahin3 1 Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry 06100 Ankara, Turkey2 non University, Faculty of Pharmacy, Department of pharmaceutical Technology, 44280, Malatya, Turkey3 Hacettepe University, Faculty of Pharmacy, Department of pharmaceutical Technology, 06100, Ankara, TurkeyABSTRACTR ivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV Spectrophotometric Method was developed for the Determination of rivaroxaban content in pharmaceutical formulations and the amount of rivaroxaban released in tablet dissolution studies. The dissolution profile of rivaroxaban was successfully determined with the validated : Rivaroxaban; UV spectroscopy; tablet dissolution, vitro testing of drug release from pharmaceutical dos age forms is a common step of routine quality control as well as an initial phase of the product development pro cess.
56 Dissolution Technologeis | NOVEMBER 2014 UV Spectrophotometric Method for Determination of the Dissolution Profile of Rivaroxaban Mustafa Çelebier1, Mustafa Sinan Kaynak2, Sacide Altınöz1,*, and Selma Sahin3 1Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry 06100 Ankara, Turkey 2İnonü University, Faculty of Pharmacy, Department of Pharmaceutical …
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In pharmaceutical dosage forms, INDEX, Dosage forms, Research Article ISSN : 0975-7384 CODEN, Pharmaceutical, Lacosamide, Sitagliptin Phosphate: Development of a, Sitagliptin Phosphate: Development of a Dissolution, Method development for the simultaneous, Method development for the simultaneous analysis, The Ph. Eur