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VA/DoD Major Depressive Disorder Clinical Practice …

VA/DoD Clinical Practice GUIDELINE FOR. THE MANAGEMENT OF Major Depressive . Disorder . Department of Veterans Affairs Department of Defense QUALIFYING STATEMENTS. The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision making. They are not intended to define a standard of care and should not be construed as one. Neither should they be interpreted as prescribing an exclusive course of management. This Clinical Practice Guideline is based on a systematic review of both Clinical and epidemiological evidence. Developed by a panel of multidisciplinary experts, it provides a clear explanation of the logical relationships between various care options and health outcomes while rating both the quality of the evidence and the strength of the recommendation.

April 2016 Page 6 of 173 . posttraumatic stress disorder (PTSD), and substance misuse are common co-occurring conditions that may worsen the existing depression and complicate treatment. ... • Improvement in quality of life and social and occupational functioning • Improvement of symptoms • Retention (keeping patients engaged in treatment ...

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