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Validation of Titration Methods - bikeitech.com

METTLER TOLEDO TitratorsValidation of Titration MethodsApplication brochure 16 Det LimResConcConf LimConf LimCalibration LineVEQEVPage 2/28 METTLER TOLEDOV alidation of Titration MethodsEditorialDear Readerthis Application Brochure provided by METTLER TOLEDO shows you how tovalidate a Titration method. The recommendations and remarks have been put to-gether by Chris Walter, Application Chemist of the Market Support AnaChem. Healso measured all the results and evaluated Validation of a method brings indeed some work, but thoughtful planning andcareful preparation limit the efforts. And you win a reliable method which you dailyapply with got the preface by courtesy of a user in the pacific region, who is a long timeexpert in method making.

Page 8/28 METTLER TOLEDO Validation of Titration Methods There are two practical ways to check a titration method for linearity: A) The regression coefficient (R 2) of the linear regression described in graph 1 must be better than a given limit, depending on the demanded accuracy for the specific determi-

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