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Vetiver Oil and Its Sedative Effect

492 Vetiver Oil and Its Sedative EffectSirinan Thubthimthed, Krittiya Thisayakorn, Ubon Rerk-am,Sinn Tangstirapakdee, and Taweesak SuntorntanasatThailand Institute of Scientific and Technological Research (TISTR, Bangkok, ThailandAbstract : The essential oil obtained by steam distillation from the roots of Vetiveria zizanioides (L.)Nash was investigated for their chemical constituents by GC and GC/MS. The major volatile componentsbelong to the sesquiterpene group such as khusimol, a-vetivone, and b-vetivone. The Sedative Effect ofvetiver oil upon inhalation in rats was studied by observing the number of crossing and rearing results showed that Vetiver oil decreased rearing motility when compared to the control words: Vetiver oil, Sedative Effect , khusimolEmail contract: Sirinan Thubthimthed INTRODUCTIONThe essential oil of Vetiver , Vetiveria zizanioides (L.))

492 Vetiver Oil and Its Sedative Effect Sirinan Thubthimthed, Krittiya Thisayakorn, Ubon Rerk-am, Sinn Tangstirapakdee, and Taweesak Suntorntanasat

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