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Warfarin and its interactions with foods, herbs and other ...
2006 Informa UK Ltd ISSN 1474-0338433 Cardiovascular & RenalWarfarin and its interactions with foods, herbs and other dietary supplementsEdith A Nutescu , Nancy L Shapiro, Sonia Ibrahim & Patricia West University of Illinois at Chicago, College of Pharmacy, Department of Pharmacy Practice, Chicago, IL 60612, USAD espite its complex pharmacokinetic and pharmacodynamic profile, warfarinis still one of the most widely used oral anticoagulant agents. Attaining opti-mal anticoagulation with this agent is clinically challenging in view of its manyfood and drug interactions . Inappropriate anticoagulation control can exposepatients to an increased risk of bleeding or thromboembolic complications,due to over and underanticoagulation, respectively.
Warfarin and its interactions with foods, herbs and other dietary supplements 434 Expert Opin. Drug Saf. (2006) 5(3) 10-hydroxywarfarin and 4′-hydroxywarfarin (minor pathway).
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