Transcription of Waters’ clinical solutions
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Waters’ clinical solutions
2015 Waters Corporation 1 Waters clinical solutions Automating and Integrating Sample Preparation with LC/MS and Software connection to the LIMS Dr. Simone Donzelli Health Sciences Business Development Manager Southern Europe 2015 Waters Corporation 2 Outline Sample Preparation Needs and Strategies Product Portfolio for Integration of Sample Prep and LC/MS Offline Sample Preparation oOffline Automated Sample Preparation System (OASPS) Product Features Applications Example of the Effects of Automated Sample Preparation 2015 Waters Corporation 3 Sample Preparation for LC/MS Prevailing attitude in many laboratories is to do as little sample prep as possible because sample prep is seen as: Costly, labor intensive and inefficient Delivering inconsistent results Requires slow and difficult method development Uses expensive sample prep consumables If sample prep is needed many labs deploy good enough techniques Dilute and Shoot LLE/ILE Protein Crash and Shoot Try to solve assay issues with LC/MS and avoid sample prep Increased instrument downtime and service requirements Increased column consumption Solvent exposure and disposal Compromised assay results 2015 Waters Corporation 4 Many LC/MS assays require or can greatly benefit from sample prep Low level analytes Poorly ionizing analytes Complex
Waters’ clinical solutions Automating and Integrating Sample Preparation with LC/MS and Software connection to the LIMS Dr. Simone Donzelli Health Sciences Business Development Manager Southern Europe ©2015 Waters Corporation 2 Outline Sample Preparation Needs and Strategies
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