Transcription of What is Cancer? - CSUN
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What is Cancer? - CSUN
1 what is cancer ? cancer is a genetic disease: Inherited cancer Sporadic cancer cancer typically involves a change in geneexpression/function: Qualitative change Quantitative change Any cancer causing genetic alteration typically results inloss of cell growth is Cancer? 3 what is Cancer? Malignant Vs. Benign growth Benign: called a tumor Well circumscribed, slow growing, non invasive, non metastatic. Malignant: called a cancer Not well organized, irregularly shaped, fast growing, infiltrativegrowth, metastatic. Initial stages of malignant cancer may typically showbenign growth; further accumulation of mutations may make it Benign tumors aretumors that cannotspread by invasionor metastasis;hence, they onlygrow locally.
ÐLack of gap junctions; Ðlack of contact inhibition ÐResistance to cell death; persistent telomerase activity ÐRapid growth; overtake population, invade other tissues. ÐAngiogenesis ÐClonal nature of cancer ÐGenomic Instability: Accumulation of successive mutations ¥A germline mutation causes a hereditary cancer.
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