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Perioperative Management of Patients with sickle Cell Disease November 29th, 2012 David Vivas, MD - History CC: RLQ pain HPI: 14 y/o female with h/o Hg SC presented to ED with 4 days h/o abdominal pain, initially diffuse but later locating to RLQ, associated with nausea, vomiting x 4 (nonbilious/nonbloody) and back pain. Patient denied fevers, diarrhea. - History PMH: SCD, multiple hospital admissions for pain crises in Jamaica PSH: None SHx: Patient recently emigrated to the US from Jamaica (2 weeks prior to presentation) FHx: Father, mother, brother with SCD NKDA - PE VS: T , HR: 125, BP: 111/69, RR: 30, SaO2: 99% AAOx3, In mod.

Sickle Cell Dz: Basic Science • Hemoglobin is a tetrameric protein consisting of 2 alpha ( α) and 2 nonalpha polypeptide chains ( ε, γ, β, δ) attached to 4

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  Cells, Hemoglobin, Sickle, Sickle cell

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