Alcohol and Medication Interactions
to alcohol-medication interactions. However, this issue still requires fur-ther investigation. Alcohol Metabolism in the Liver The liver is the primary site of alcohol metabolism. Alcohol circulating in the blood is transported to the liver, where it is broken down by several enzymes, the most important of which are ADH and cytochrome P450 ...
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pubs.niaaa.nih.govenzymes cytochrome P450 and catalase (see below). In general, alcohol meta bolism is achieved by both oxidative pathways, which either add oxygen or . remove hydrogen (through pathways involving ADH, cytochrome P450, and catalase enzymes), and nonoxidative pathways. Oxidative Pathways . As shown in Figure 1, ADH, cytochrome