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Chapter 14. Enzyme Kinetics

Chapter 14. Enzyme Kinetics

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M is a measure of catalytic efficiency [E][S] [S] [E] [S] [S] [S] ... (Dihydrofolate reductase inhibitor, anticancer drug ) Modes of the reversible inhibition • Competitive inhibitors – Binds to the substrate binding site • Uncompetitive inhibitors – Binds to enzyme-substrate complex

  Efficiency, Inhibitors

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