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HIGHLIGHTS OF PRESCRIBING INFORMATION Diarrhea ...

HIGHLIGHTS OF PRESCRIBING INFORMATION Diarrhea ...

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• •Dose interruptions and/or dose reductions are recommended based on individual safety and tolerability. (2.3) • Hepatic impairment: Reduce starting dose to 80 mg in patients with severe ... of potential risk to a fetus and to use effective contraception. (5.3, 8.1, 8.3)

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