Information for the package leaflet regarding polysorbates ...
74 containing 10 mg/kg PS 80 compared to a formulation without polysorbate and benzyl alcohol. In 75 dogs, bolus doses : ≥ 10 mg/kg of PS 80 alone lead to depression of the cardiac conduction and 76 hypotension. Thus from the totality of preclinical and clinical data a threshold of 10 mg/kg (given as
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