Ingenuity Pathway Analysis (IPA
Analysis, a component of IPA Advanced Analytics, uncovers multi-level causal relation-ships relevant to experimental data by expand-ing upstream analysis to include regulators that are not directly connected to targets in the analyzed dataset. Another Advanced Analytics Figure 2. Interactive analysis of plausible upstream regulators and networks.
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Ingenuity Upstream Regulator Analysis in IPA®
pages.ingenuity.com6 and the z‐score statistic is given by: V L T ê ë L Ü T Ü Ü 6 This latter formula is used in IPA to compute the activation z‐score of the transcriptional regulator. USING THE ACTIVATION Z‐SCORE TO INDEPENDENTLY CALL UPSTREAM REGULATORS Using the activation z‐score to identify upstream regulators independent of the overlap p‐value is based on the
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