Lecture 7: Hypothesis Testing and ANOVA
•The null hypothesis is that the means are all equal •The alternative hypothesis is that at least one of the means is different –Think about the Sesame Street® game where three of these things are kind of the same, but one of these
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Lecture 10: Multiple Testing - UW Genome Sciences
www.gs.washington.eduWhy Multiple Testing Matters Genomics = Lots of Data = Lots of Hypothesis Tests A typical microarray experiment might result in performing 10000 separate hypothesis tests.
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www.gs.washington.edusource for extracting DNA because they are easy to pulverize and contain enzymes called pectinases and cellulases that help to break down cell walls. And most important, strawberries have eight copies of each chromosome (they are octoploid), so there is a lot of DNA to isolate. The purpose of each ingredient in the procedure is as follows:
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www.gs.washington.edu•Before data is collected, we regard observations as random variables (X 1,X 2,…,X n) •This implies that until data is collected, any function (statistic) of the observations (mean, sd, etc.) is also a random variable •Thus, any statistic, because it is a random variable, has a probability distribution - referred to as a sampling ...
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Lecture 5: Estimation - University of Washington
www.gs.washington.eduBayesian Estimation: ÒSimpleÓ Example ¥I want to estimate the recombination fraction between locus A and B from 5 heterozygous (AaBb) parents. I examine 30 gametes for each and observe 4, 3, 5, 6, and 7 recombinant gametes in the Þve parents. What is the mle of the recombination fraction? ¥Tedious to show Bayesian analysis. LetÕs simplify ...
Lecture 9: Linear Regression - University of Washington
www.gs.washington.eduLecture 9: Linear Regression. Goals • Linear regression in R •Estimating parameters and hypothesis testing ... •Previous coding would result in colinearity •Solution is to set up a series of dummy variable. In general for k levels you need k-1 dummy variables x 1 …
1. Plasmid structure 2. Plasmid replication and copy ...
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