Modified-release preparations
a laser-drilled hole e.g. Volmax, Adalat LA. pH sensitive coating The formulation is coated with a polymer of pH dependent solubility for site specific delivery. This can either avoid drug release in the stomach (enteric coating) e.g. Nu-Seals Aspirin, or specifically deliver drug to the colon e.g. Asacol. Table 1. Some mechanisms of modified ...
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