SAMHSA Opioid Overdose Toolkit
that usually is the cause of overdose deaths. 2 . Naloxone is an appropriate response for all opioid overdose events, including fentanyl -involved overdoses. Multiple doses of naloxone may be required when the overdose results from ingestion of large amounts of opioids or potent opioids such as fentanyl, carfentanil, or other opioid analogs. 4
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