Structure-Function of the Glucagon Receptor Family …
180 P. L. BRUBAKER AND D. J. DRUCKER TABLE 1 The amino acid sequences of human glucagon, GLP-1, GLP-2, and GIP Glucagon HSQGTFTSDYSKYLDSRRAQDFVQWLMNT GLP-1 HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
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A new glucagon and GLP-1 co-agonist eliminates …
www.glucagon.comgluconeogenesis and glycogenolysis, whereas GLP-1 acts by multiple mechanisms to lower glucose, most notably by enhancing glucose-stimulated insulin synthesis and secretion at the pancreas16.
Pharmacology, Physiology, and Mechanisms of …
www.glucagon.comCell Metabolism Review Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action Jonathan E. Campbell 1and Daniel J. Drucker ,* 1Department of Medicine, Samuel LunenfeldResearchInstitute,MountSinai Hospital,Universityof Toronto,Toronto,ON M5G 1X5,Canada *Correspondence: [email protected]
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www.glucagon.comGlucagon-like Peptide-1 Receptor Signaling Modulates Cell Apoptosis* Received for publication, September 13, 2002, and in revised form, October 22, 2002
Human glucagon gene promoter sequences …
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