Viral Replication: Basic Concepts - Columbia University
Native Form Fusion peptide HR1 HR2 Fusion Intermediate T20----- - ----- -- - - - - - - - - -----“Ensnared” Transition State Intermediate Conformation Fusion Blockade Membrane Fusion Core Structure T1249 Mechanism of T20/T1249 Mediated Fusion Inhibition Modified from Weissenhorn et al., Nature 387, 426-430 (1997) and Furuta et al., Nature ...
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