Company Profile Deb22Mar(1) - Jazz Pharmaceuticals

1 Company PROFI L EOu r mi s s ion i s t o i mp r ove p a t i e n t s l i v e s b y i d e n t i f y i n g , d evelopi n g , and c o mmer c i a lizi n g me a n i n g f u l p r o d u c t s t h a t a d d r e s s u n me t me d i c al needs .Who We Ar eWhere there s a will, there s a way. Patients are our a z z Pharmac e u t i c a l s p l c i s a n inte r n a t ional b ioph armac e u t i c a l c o mp a n y f o cuse d o n i mp r o v i n g p a t ient s l i v e s b y i dent i f y i n g , d e v elopi n g , a n d c o mmer c i a lizi n gme anin g f u l p r o d u c t s t h a t a d d r e ss u n me t me d i c a l n eeds.

2 We have a diverse portfolio of products and product candidates, with a focus in theareas of sleep and hematology/oncology. We also support commercial products inother therapeutic areas where we can meaningfully address serious medical part of our unwavering commitment to improve patients lives, we are continuingto expand our commercial product portfolio and our research and developmentpipeline in therapeutic areas that can leverage our unique expertise. We do thisthrough a growth strategy of growing sales of the existing medicines in our portfolio;acquiring commercial products or product candidates that are in late-stagedevelopment; and pursuing focused development of our pipeline of h a v e a s t r o n g p a t ient - f o cuse d c ultu r e a t J a z z Ph armac e u t i c a l s t h a t o u r e mp l o y e e s b e l i eve i n a n d p u r s u e e v e r y d a y.

3 I t i s c learly i dent i fi e d t h r o u g h o u r mi s s ion, v i s ion a n d c o r e values . Eac h member of our team makes integral c ontr ibutions and is wor king toward a c ommon goal to improve patients' lives. Ever y thing we do at Ja z z Phar mac eutic als is focused on three things: Putting patients f ir st Being a great plac e to wor k Living our c ore values integr it y, c ollaboration, passion, pur suit of exc ellenc e and innovationOu r Cu l t u r eWe h a v e a d i v e r s e p o r t f o l i o o f p r o d u c t s i n o u r t h e r a p e u t i c a r eas o f f o cus: s l e e p a n d h e ma t olog y/o n c o l o g y.

4 We also support commercial products in therapeutic areas where we canmeaningfully address serious medical needs. Our products are reaching patientsin over 80 o duct sAt Jazz Pharmaceuticals , we strive to identify and develop new, meaningfulproducts that fill significant unmet medical needs of patients. We are activelyexpanding global R&D capabilities and advancing our clinical pipeline intherapeutic areas that leverage our research and development program currently includes clinical developmentprograms in the areas of sleep and hematology/oncology for new productcandidates, line extensions for existing products and the generation of additionalclinical data for existing products.

5 Re s e a r c h a n d Developme n tB r u c e C . C oz add Ch airm an an d Ch i ef E xe c ut i ve O f f i c e rRu s sell J . C ox E xe c ut i ve V i c e Pr e s i dent an d Ch i ef O p e r at in g O f f i c e rS u z anne S awoc h ka H o o p e r E xe c ut i ve V i c e Pr e s i dent an d G enera l C o unse lH e a t h e r Mc G a u g h ey S e ni o r V i c e Pr e s i dent , H um an Resour c e sIain Mc G ill S e ni o r V i c e Pr e s i dent , J a z z Ph ar m ac e ut i c als Eur o p e an d Re st of Wo r l dRo b e r t Mc Ka g u e S e ni o r V i c e Pr e s i dentan d Chi ef C o m p li ance O f f i c e rMi c h a e l P.

6 Mille r S e ni o r V i c e Pr e s i dent , U S C o m m e r c i a lKa re n S m i t h, M. D. , P h . D., , G lobal H e ad of Resear c h an d D evelopm e nt an d Ch i ef M e di c a l O f f i c e rPa u l Tre a c y S e ni o r V i c e Pr e s i dent , Te c hnic a l O p e r at i o ns Matthew Young E xe c ut i ve V i c e Pr e s i dent an d Chi ef Financi a l O f f i c e rOu r leadersh i p t e a m h a s a pr oven trac k r e c o r d o f s u c cess f u l l y d evelopi n g a n d c o mmer c i a lizi n g t h e r a p e utics a n d c r eating p a t ient p r o g r a ms t h a t r e s ult i n b e t t e r p a t ient c a r e.

7 At the same time, they ve demonstrated their abilit y to drive shareholder value and built Jaz z Phar mac eutic als into an employer of choic e. The following individuals c omprise Jaz z Phar mac eutic als E xecutive Commit tee. See Jaz zPhar mac eutic om for biographies and a listing of the c ompany s Board of rLeadersh i pOu r Ph i l a nthr o p i c Responsi b ilit yAt Jazz Pharmaceuticals , we view our corporate giving as an opportunity for us tohelp improve patients lives by filling unmet needs, to demonstrate our commitmentto the communities we serve by building powerful collaborations, and to make animpact through meaningful investments in organizations, initiatives and causes thatreflect our mission, values.

8 And strategic is committed to supporting programs through educational grants, sponsorships andresearch that benefits patients and the scientific or medical community. These supportedprograms are healthcare-related and consistent with Jazz Pharmaceuticals therapeuticsareas of focus. We are also committed to being an exemplary corporate citizen andcontributing to the well-being of the communities in which we live and Areas of Focus Include: Healthcare-related charitable support Philanthropic charitable support Independent medical education 2003 Ja z z Phar mac eutic als founded 2003/2004 M anagement team assembled /c apit al raised 2005 Ac quired O r phan M edic al and its produc t, xyrem 2007 L aunc h of Luvox CR 201 2 Merger with Azur Pharma, which changed Jazz Pharmaceuticals in manyways, including providing new global headquarters in Dublin, Ireland.

9 Brining in new employees and new members of our management team andexpanding our product offerings by bringing Prialt into the Company 201 2 Ac quired EUSA Phar ma, whic h ex tended our product offeringsto include Erwinaze /Erwinase and helped us establish our Europeancommercial infrastructure 201 3 Lic ense agreement with C onc er t Phar mac eutic als for the r ights to JZP- 3 8 6 201 4 Broke ground on manufac tur ing fac ilit y in Ireland 201 4 Ac quired r ights to JZP-110 f rom Aerial Bio Phar ma 201 4 Ac quired G entium, whic h added Def itelio (def ibrotide) to our produc t por t folio.

10 European c ommerc ial launc h of Def itelio 201 4 Ac quired r ights to def ibrotide in the A mer ic as f rom Sigma -Tau Phar maOu rHi s t o r y 201 5 JZP-110 Phase 3 clinical program initiated 201 6US launch of Defitelio (defibrotide sodium) The name "Jazz Pharmaceuticals " was inspired by the talented jazz musicians whocome together each a musical specialist with an individual style to make musicin concert that is greater than the sum of its parts. Each talented member of our team,working collaboratively, comes together to contribute to a common goal: improvingpatients a t s i n Ou r Na me ?