Volume 62 Number 12 December 2021

1 Volume 62 Number 12 December 2021 SNMMI NEWSLINE11N2021 SNMMI Highlights Lecture: NeuroscienceJulie Price18 NABNM: Interim Report on Provisional Requirements forRadionuclide TherapyGeorge M. Segall19 NSNMMI Leadership Update: SNMMI Mid-Winter and ACNMA nnual Meeting Convene In-PersonVirginia Pappas20 NNewsbriefsDISCUSSIONS WITH LEADERS1657 Molecular Imaging Leadership in Academia and IndustryMark Mintun and David MankoffTHE STATE OF THE ART1660 Radionuclide Therapy in Prostate Cancer: From Standaloneto Combination PSMA TheranosticsShahneen Sandhu, Christina Guo, and Michael S. HofmanHOT TOPICS1669 Radioembolization Versus Bland or Chemoembolization forLiver-Dominant Neuroendocrine Tumors: Is It an Either/OrQuestion?Jonathan Strosberg, Ghassan El-Haddad, Taymeyah Al-Toubah,Diane Reidy-Lagunes, Etay Ziv, Armeen Mahvash, Arvind Dasari,Philip A. Philip, and Michael C. SoulenFOCUS ON MOLECULAR IMAGING1672 Building the Bridge: Molecular Imaging Biomarkers for 21stCentury Cancer TherapiesMark A.

2 Sellmyer, Iris K. Lee, and David A. MankoffONCOLOGYC linical1677 Determining the Axillary Nodal Status with 4 CurrentImaging Modalities, Including18F-FDG PET/MRI, in NewlyDiagnosed Breast Cancer: A Comparative Study UsingHistopathology as the Reference StandardJanna Morawitz, Nils-Martin Bruckmann, Frederic Dietzel,Tim Ullrich, Ann-Kathrin Bittner, Oliver Hoffmann,Svjetlana Mohrmann, Lena H aberle, Marc Ingenwerth,Lale Umutlu, et Value of Postinduction ChemotherapyVolumetric PET/CT Parameters for Stage IIIA or IIIBNon Small Cell Lung Cancer Patients Receiving DefinitiveChemoradiotherapyMaja Guberina, Christoph P ottgen, Martin Metzenmacher,Marcel Wiesweg, Martin Schuler, Clemens Aigner,Till Ploenes, Lale Umutlu, Thomas Gauler,Kaid Darwiche, et Radioembolization Versus SystemicTreatment for Hepatocellular Carcinoma withMacrovascular Invasion: Analysis of the NationalCancer DatabaseJoseph C. Ahn, Marie Lauzon, Michael Luu, Marc L. Friedman,Kambiz Kosari, Nicholas Nissen, Shelly C.

3 Lu, Lewis R. Roberts,Amit G. Singal, and Ju Dong Yang1702 Minimal Extrathyroidal Extension in Papillary ThyroidMicrocarcinoma Is an Independent Risk Factor for RelapseThrough Lymph Node and Distant MetastasesRobert Seifert, Michael Sch afers, Barbara Heitplatz, Laura Kerschke,Burkhard Riemann, and Benjamin VISION to Nuclear Medicine:Accelerating Evidence and Changing Paradigms withTheranosticsMichael S. Hofman1712 Symptom Diaries of Patients with Midgut NeuroendocrineTumors Treated with177Lu-DOTATATEJ onathan R. Strosberg, Rajaventhan Srirajaskanthan,Ghassan El-Haddad, Edward M. Wolin, Beth A. Chasen,Matthew H. Kulke, David L. Bushnell, Martyn E. Caplin,Richard P. Baum, Andrew E. Hendifar, et Efficacy PET/CT and Impacton Management in Patients with Biochemical Recurrence ofProstate Cancer After Radical Prostatectomy and BeforePotential Salvage TreatmentIsabel Rauscher, Amir Karimzadeh, Kilian Schiller, Thomas Horn,Calogero D Alessandria, Charlott Franz, Hannah W orther,Noemi Nguyen, Stephanie E.

4 Combs, Wolfgang A. Weber, et Phase II, Open-Label Study to Assess Safety andManagement Change Using 68Ga-THP PSMA PET/CT inPatients with High- Risk Primary Prostate Cancer orBiochemical Recurrence After Radical Treatment: ThePRONOUNCED StudyAsim Afaq, Heather Payne, Reena Davda, John Hines, Gary Cook,Marie Meagher, Dimitrios Priftakis, Victoria S. Warbey, Anand Kelkar,Clement Orczyk, et Detection of18F-PSMA-1007 in the Prostate Gland inPatients with Prostate Cancer Using ProstatectomySpecimens as Reference MethodElin Tr ag rdh, Athanasios Simoulis, Anders Bjartell, and Jonas J ogi1741 Assessing Response to177Lu-PSMA Radioligand TherapyUsing Modified PSMA PET Progression CriteriaKerstin Michalski, Claudius Klein, Tonio Br uggemann,Philipp T. Meyer, Cordula A. Jilg, and Juri Ruf1747nBRIEF PET for the Assessmentof Metastatic Hormone-Sensitive Prostate Cancer Volumeof DiseaseFrancesco Barbato, Wolfgang P. Fendler, Isabel Rauscher,Ken Herrmann, Axel Wetter, Justin Ferdinandus, Robert Seifert,Michael Nader, Kambiz Rahbar, Boris Hadaschik, et THERAPYB asic1751nFEATURED BASIC SCIENCE with Combination Epithelial Sodium ChannelBlockadeDiane S.

5 Abou, Amanda Fears, Lucy Summer, Mark Longtine,Nadia Benabdallah, Ryan C. Riddle, David Ulmert, JeffM. Michalski,Richard L. Wahl, Denise Chesner, et of the Effect of Three Different DietaryModificationsonMyocardialSuppress ion in18F-FDG PET/CTEvaluation of Patients for Suspected Cardiac SarcoidosisCan Oz utemiz, Yasemin Koksel, Jerry W. Froelich, Nathan Rubin,Maneesh Bhargava, Henri Roukoz, Rebecca Cogswell,Jeremy Markowitz, David M. Perlman, and Daniel Steinberger1768 MRI-Guided Motion-Corrected PET Image Reconstructionfor Cardiac PET/MRIC amila Munoz, Sam Ellis, Stephan G. Nekolla, Karl P. Kunze,Teresa Vitadello, Radhouene Neji, Rene M. Botnar, Julia A. Schnabel,Andrew J. Reader, and Claudia PrietoNEUROLOGYC linical1775nFEATURED ARTICLE OF THE : Quantification of Parkinson Disease MetabolicNetworks and Nigrostriatal Dopaminergic Dysfunction in aSingle Imaging SessionShichun Peng, Chris Tang, Katharina Schindlbeck, Yaacov Rydzinski,Vijay Dhawan, Phoebe G.

6 Spetsieris, Yilong Ma, and David Eidelberg1783 Frontal Hypometabolism in Neurocognitive Disorder withBehavioral DisturbanceChristine Bastin, Mohamed Ali Bahri, Claire Bernard, Roland Hustinx,and Eric SalmonBasic1789A Noninvasive Method for Quantifying Cerebral MetabolicRate of Oxygen by Hybrid PET/MRI: Validation in a PorcineModelLucas Narciso, Tracy Ssali, Linshan Liu, Heather Biernaski, John Butler,Laura Morrison, Jennifer Hadway, Jeffrey Corsaut, Justin W. Hicks,Michael C. Langham, et IMAGINGB asic1797 Mesothelin/CD3 Half-Life Extended Bispecific T-CellEngager Molecule Shows Specific Tumor Uptakeand Distributes to Mesothelin and CD3-ExpressingTissuesFrans V. Suurs, Grit Lorenczewski, Julie M. Bailis,Sabine Stienen, Matthias Friedrich, Fei Lee, Bert van der Vegt,Elisabeth de Vries, Derk Jan A. de Groot, andMarjolijn N. Lub-de HoogeRADIOBIOLOGY/DOSIMETRYB asic1805 Patient Size-Dependent Dosimetry Methodology Applied to18F-FDG Using New ICRP Mesh PhantomsLukas M.

7 Carter, Chansoo Choi, Simone Krebs, Bradley J. Beattie,Chan Hyeong Kim, Heiko Schoder, Wesley E. Bolch, andAdam L. KesnerINFECTIOUS DISEASEC linical1815 Appropriate Use Criteria for the Use of Nuclear Medicine inMusculoskeletal Infection ImagingChristopher J. Palestro, Alicia Clark, Erin E. Grady, Sherif Heiba,Ora Israel, Alan Klitzke, Charito Love, Mike Sathekge, Treves Ted,and Tracy L. YarbroughLETTERS TO THE EDITOR1832 Houdini s Illusions: Some Acts Are Not What They Seemto BeRoelof J. Bennink, Mathias Prokop, Andor W. J. M. Glaudemans,Liesbeth Peters-Bax, Jasper H. G. Helthuis, Arthur Adams,Peter R. Kornaat, Adriaan A. Lammertsma, andLenka M. Pereira Arias-Bouda1833 Cut Point Identification of Continuous Biomarkers:A Challenge That Goes Beyond Statistical AspectsPaulo Schiavom DuarteDEPARTMENTS10 AThis Month in JNM