KinaseConsensusPhosphorylation SiteSpecificityAcidicDEAsp/GluBasicKRLys /ArgWeak BasicNQAsn/GlnWeak polarMMetHydrophobicFILVYPhe/Ile/Leu/Val /TyrKinkPProPolarSTSer/ThrPhospho-AApSpT pSer/pThrPhospho-AApYpTyrNeutralAGAla/Gl yAny
www.kinexus.ca Protein Kinase -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 CLK1 . KR . KR . KR . pSpT . . R . . PKC-eta A R . . R KR RpSpT F R R . . PKC-alpha .
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1 KinaseConsensusPhosphorylation SiteSpecificityAcidicDEAsp/GluBasicKRLys /ArgWeak BasicNQAsn/GlnWeak polarMMetHydrophobicFILVYPhe/Ile/Leu/Val /TyrKinkPProPolarSTSer/ThrPhospho-AApSpT pSer/pThrPhospho-AApYpTyrNeutralAGAla/Gl yAny
Endocrinology & Metabolism International Journal Tyrosine Kinase Inhibitors for the Treatment of Thyroid Cancer: Present and Future Volume 2 Issue 4 - 2015
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476 Adopted: 21st July 1997 1/10 OECD GUIDELINE FOR THE TESTING OF CHEMICALS In Vitro Mammalian Cell Gene Mutation Test INTRODUCTION 1. The in vitro mammalian cell gene mutation test can be used to detect gene mutations