Nutrient Sensing and Metabolic Signaling - …

1 16 May 2018 Nutrient Sensing and Metabolic Signaling August 5-10, 2018 Snowmass, Colorado Organizers: Blake Rasmussen, PhD University of Texas Medical Branch Galveston, TX Chris Adams, MD, PhD University of Iowa Iowa City, IA Sunday, August 5, 2018 Time Title/Topic Event Speaker 4:00 9:00 Conference Registration 6:00 7:00 Welcome Reception 7:00 8:00 DINNER 8:00 8:15 Welcome Blake Rasmussen & Chris Adams 8:15 9:30 Keynote Address A Novel Sensing Mechanism Controlling ER-associated Degradation of HMG-CoA Reductase Russell DeBose-Boyd, PhD University of Texas Southwestern Medical Center Monday, August 6, 2018 Time Title/Topic Event Speaker 7:30 12:00 Conference Registration 7:30 9:00 BREAKFAST 9:00 12:00 Scientific Session 1: Glucose Sensing Pathways Chair: Reuben Shaw 9:00 9:30 AMPK Regulation of Fat Metabolism and Insulin Sensitivity Greg Steinberg, PhD McMaster University 9:30 9:45 Short Talk Selected from Abstracts 9:45 10:15 Exercise-Induced Mitophagy in Skeletal Muscle via AMPK Zhen Yan, PhD University of Virgina 10:15 10:45 COFFEE BREAK 16 May 2018 10:45 11:15 Regulation of AMPK in Energy Metabolism David Carling, PhD University College, London 11:15 11:30 Short Talk Selected from Abstracts 11:30 12:00 LKB1-AMPK Regulation of Glucose Metabolism Reuben Shaw, PhD Salk Institute 12:00 1:00 LUNCH and Meet the Experts Session 1:00 4:00 Free time 4:00 6:00 Conference Registration 4:00 6.

2 00 Poster Session 1 6:00 7:00 DINNER 7:00 9:30 Scientific Session 2: Cholesterol Sensing Pathways Chair: Russell Debose-Boyd 7:00 7:30 Regulation of SREBP Pathway in Cancer Peter Espenshade, PhD Johns Hopkins University 7:30 7:45 Short Talk Selected from Abstracts 7:45 8:15 Role of ABCG1 in Modulating Sterol and Lipid Homeostasis Elizabeth Tarling, PhD UCLA 8:15 8:45 Protein Sensors for Membrane Cholesterol Arun Radhakrishnan, PhD UT Southwestern Medical Center 8:45 9:00 Short Talk Selected from Abstracts 9:00 9:30 Structural Basis for TRPML-mediated Lysosomal Lipid Accumulation Xiaochun Li, PhD UT Southwestern Medical Center Tuesday, August 7, 2018 Time Title/Topic Event Speaker 7:30 12:00 Conference Office is Open 7:30 9:00 BREAKFAST 9:00 12:00 Scientific Session 3: Amino Acid Sensing Pathways 1 Chair: Tracy Anthony 9:00 9:30 Nutrient Stress Signals and Translational Control Ron Wek, PhD Indiana University 9:30 9:45 Short Talk Selected from Abstracts 9:45 10:15 Transcription Factor Networks Associated with Amino Acid Insufficiency Michael Kilberg, PhD University of Florida 10:15 10:45 COFFEE BREAK and GROUP PHOTO 10:45 11:15 Unique Cellular Response to Hyperammonemic Stress Srinivasan Dasarathy, MD Cleveland Clinic 11:15 11:30 Short Talk Selected from Abstracts 11:30 12:00 eIF2 Kinase Signaling in Health and Disease Tracy Anthony, PhD Rutgers University 12:00 1.

3 00 LUNCH and Meet the Experts Session 1:00 2:30 Career Development Workshop 2:30 6:00 Free time 4:00 6:00 Conference Office is Open 6:00 7:00 DINNER 7:00 9:30 Scientific Session 4: Amino Acid Sensing Pathways 2 Chair: Brendan Manning 7:00 7:30 Amino Acid Sensing by mTORC1 David Sabatini, MD, PhD Whitehead Institute 7:30 7:45 Short Talk Selected from Abstracts 16 May 2018 7:45 8:15 mTOR/S6K1 Regulation and Signaling John Blenis, PhD Weill Cornell Medicine 8:15 8:45 Metabolic Transitions in Amino Acid Metabolism Heather Christofk, PhD UCLA 8:45 9:00 Short Talk Selected from Abstracts 9:00 9:30 mTORC1 links Nutrient Sensing to Anabolic Metabolism Brendan Manning, PhD Harvard University Wednesday, August 8, 2018 Time Title/Topic Event Speaker 7:30 12:00 Conference Office is Open 7:30 9:00 BREAKFAST 9:00 12:00 Scientific Session 5: Nutrient Sensing Pathways in Skeletal Muscle Chair: Chris Adams 9:00 9:30 Amino Acid Sensing in Human Skeletal Muscle Blake Rasmussen, PhD University of Texas Medical Branch 9:30 9:45 Short Talk Selected from Abstracts 9:45 10:15 Role of Intramuscular Lipids in Muscle Anabolic Resistance Sue Bodine, PhD University of Iowa 10:15 10:30 COFFEE BREAK 10:30 11:00 mTORC1 Signaling in Skeletal Muscle Markus Ruegg, PhD University of Basel, Switzerland 11:00 11.

4 30 Leucine Sensing in Skeletal Muscle Scot Kimball, PhD Penn State College of Medicine 11:30 12:00 Role of ATF4 in Skeletal Muscle Atrophy Chris Adams, MD, PhD University of Iowa 12:00 1:00 LUNCH and Meet the Experts Session 1:00 4:00 Free time 4:00 6:00 Conference Office is Open 4:00 6:00 Poster Session 2 6:00 7:00 DINNER 7:00 9:30 Scientific Session 6: Nutrient Sensing Pathways in Diabetes & Obesity Chair: Bret Goodpaster 7:00 7:30 Role of Skeletal Muscle & Mitochondria in Nutrient Sensing in Obesity & Diabetes Jared Rutter, PhD University of Utah 7:30 7:45 Short Talk Selected from Abstracts 7:45 8:15 Role of Liver/Hepatic Metabolism in Nutrient Sensing in Obesity & Diabetes Timothy Osborne, PhD Sanford Burnham Prebys Medical Discovery Institute 8:15 8:45 Alterations of Fuel Substrate Preferences in the Failing Heart Rick Vega, PhD Translational Research Institute for Metabolism & Diabetes 8:45 9:00 Short Talk Selected from Abstracts 9:00 9:30 Role of Nutrient Sensing in Human Obesity & Diabetes Bret Goodpaster, PhD Translational Research Institute of Florida Hospital 16 May 2018 Thursday, August 9, 2018 Time Title/Topic Event Speaker 7:30 12:00 Conference Office is Open 7:30 9:00 BREAKFAST 9:00 12:00 Scientific Session 7: Nutrient Sensing Pathways in the Liver Chair: Jay Horton 9:00 9.

5 30 Role of microRNAs in Regulating Lipoprotein Metabolism and Athersclerosis Kathryn Moore, PhD New York University 9:30 9:45 Short Talk Selected from Abstracts 9:45 10:15 ANGPTLs: at the Interface of Lipoprotein Metabolism and Energy Homeostasis Helen Hobbs, MD UT Southwestern Medical Center 10:15 10:30 COFFEE BREAK 10:30 11:00 Proteomic Approaches to Studying Lipid Dysfunction in Liver Chris Newgard, PhD Duke University 11:00 11:30 Role of Calcium-IP3R-CaMKII Pathway in Obesity and Insulin Resistance Ira Tabas, MD, PhD Columbia University 11:30 12:00 Contribution of Transcriptional Regulators to the Etiology of Steatosis Jay Horton, MD UT Southwestern Medical Center 12:00 12:30 Business Meeting 12:30 BOXED LUNCH TO GO 12:30 5:30 Group Activity (Whitewater Rafting) 5:30 6:30 DINNER 6:30 Free time Snowmass Free Music Series Friday, August 10, 2018 Time Title/Topic Event 7:30 12:00 Conference Office is Open 7:30 9:00 BREAKFAST 9:00 12:00 Scientific Session 8: Nutrient Sensing Pathways in the Brain Chairs: Laurent Gautron & Joel Elmquist 9:00 9:30 Role of Vagal GPCR Signaling in Metabolism and Inflammation Laurent Gautron, PhD UT Southwestern Medical Center 9:30 9:45 Short Talk Selected from Abstracts 9:45 10:15 Role of Central Prolyl Carboxypeptidase in Regulating Metabolism Sabrina Diano, PhD Yale University 10:15 10:45 COFFEE BREAK 10:45 11.

6 15 The Role of Intestinal Remodeling in the Metabolic Success of Bariatric Surgery Darleen Sandoval, PhD University of Michigan 11:15 11:30 Short Talk Selected from Abstracts 11:30 12:00 SF-1 in the Hypothalamus: A Molecular Link Between Energy Balance & Exercise Joel Elmquist, PhD UT Southwestern Medical Center 12:00 LUNCH TO GO and DEPARTURES END OF CONFERENCE 16 May 2018 For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814