Transcription of 3）胞状奇胎診断のup-to-date - jsog.or.jp
1 2009 9 N 321. 4 . 3 up-to-date .. 1962 .. 1 . hCG .. hCG multivesicular pattern .. 20 .. 80 . 4 .. Up-to-date Diagnosis and Management of Hydatidiform Mole Takashi OHBA. Department of Reproductive Medicine and Surgery, and Gynecology, Kumamoto University, Kumamoto Key words : Hydatidiform mole Ultrasonography hCG Placental mesenchymal dysplasia !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! N 322 61 9 . 1 . 1,325 42 .. 16 26 . 7 .. 2 .. 1a b .. 1c 1d . double sac sign . hCG . hCG .. DNA .. 3 .. !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! 2009 9 N 323. hCG .. hCG 100 mIU"mL 2 . 4 . DNA P57" KIP2 .. hCG . 4 " . hCG 1,000. mIU"mL 4 . hCG 25mIU"mL 8 10 . 3 hCG " mL .. 1990 . Placental mesenchymal dysplasia PMD PMD 4,000 . 5,000 1.
2 PMD . multivesicular pattern . PMD . 1 PMD . PMD 1. di ploi d / t ri ploi d di ploi d t ri ploi dyI. UGR,I. UFD BWS 2. 20% I. UGR. 20% IUFD. 30% . hCG / 40% . AFP . USG/. MRI mul ti vesi cle mul ti vesi cle vesi cle .. t rophobl ast t rophobl ast . p57/. KIP2 cyt otr ophobl ast cyt otr ophobl ast . / / .. 1. PMD pl acent almesenchymaldysplasi a 2. BWS Beckwi th- Wiedemannsyndr ome !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! N 324 61 9 . 1 PMD hCG .. MRI multivesicular PMD. vesicle .. hCG .. hCG. PMD .. PMD .. 1 . 1995 7 51. 2 Rua S, Comino A, Fruttero A, Abrate M. DNA flow cytometric analysis of abor- tion. A simple method for detection of triploidy and tetraploidy in the tro- phoblastic cells. Pathologica 1995 ; 87 : 107 111.
3 3 Berkowitz RS, Goldstein DP, Bernstein MR. Natural history of partial molar pregnancy. Obstet Gynecol 1985 ; 66 : 677 681. 4 Fukunaga M. Early partial hydatidiform mole : prevalence, histopathology, DNA ploidy, and persistence rate. Virchows Arch 2000 ; 437 : 180 184. 5 Seckl MJ, Fisher RA, Salerno G, Rees H, Paradinas FJ, Foskett M, Newlands ES. Choriocarcinoma and partial hydatidiform moles. Lancet 2000 ; 356 : 36 39. 6 . 2008 26 381 386. 7 2000 52 988 . 1007. 8 2009 76 . 282 287. 9 Sebire NJ. Gestational trophoblastic neoplasia. In : Ultrasonography in Ob- stettics and Gynecology. Callen PW (eds), PA : Elsevier, 2008 ; 951 967. 10 2002. !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
