Transcription of 悪性リンパ腫および類縁疾患 malignant lymphoma and other …
1 444 22 . malignant lymphoma and other hematopoietic tumors . malignant lymphoma . cuta- . neous lymphoma Hodgkin . pri- mary cutaneous lymohoma . secondary cu- taneous lymphoma .. 2005 WHO EORTC . T NK B.. T NK cutaneous T cell lymphoma CTCL NK-cell lymphoma . mycosis fungoides MF . S zary S zary syndrome SS . T / adult T cell leukemia / lymphoma ATLL . CD30 primary cutaneous CD30 T-cell lymphoproliferative disorders . primary cutaneous anaplastic large cell lymphoma . lymphomatoid papulosis . T subcutaneous panniculitis-like T cell lymphoma . NK/T extranodal NK/T-cell lymphoma , nasal type . hydroa vacciniforme-like lymphoma . 22 g /d T primary cutaneous g /d T-cell lymphoma . CD8 T . primary cutaneous CD8 aggressive epidermotropic cytotoxic T-cell lymphoma . CD4 T primary cutaneous CD4 small/medium T-cell lymphoma . T peripheral T-cell lymphoma , not otherwise specified.
2 B cutaneous B cell lymphoma CBCL . B primary cutaneous marginal zone B-cell lymphoma . primary cutaneous follicle center lymphoma PCFCL . B primary cutaneous diffuse large B-cell lymphoma , leg type . B primary cutaneous diffuse large B-cell lymphoma , other . B intravascular large B-cell lymphoma . precursor hematologic neoplasm . CD4 /CD56 hematodermic neoplasm, blastic NK-cell lymphoma Kim YH, et al. Blood 110 479, 2007 . A T 445. 90 T T .. HE . T TCR .. Ig TCR IL-2 . soluble IL-2 receptor sIL-2R . Ig . CT PET, .. LDH IL-2 MEMO . HTLV-1 . EBV .. A T cutaneous T cell lymphoma CTCL.. 1 mycosis fungoides MF. T .. 3 . 22.. 10 .. erythematous stage patch stage .. Gibert .. mycosis fungoides .. 446 22 .. 15 .. plaque stage infiltrative stage . a b c d e f g h i j k l m n o p .. tumor stage .. stage of visceral dissemination . 1. 2 .. a b c d e f g h i kj l m n o p.
3 Mycosis fungoides . a b folliculotropic MF .. 22.. s microabscess, . Pautrier'.. CD4 T . CD3 , CD4 , CD5 , CD20 T CD7 . CD26 .. A T 447. a b a c d b e c df a g eb hf c gi d hj e ki f jl g m kh nl i o j m pk n o l pm a b c d e f g h i j a b c d e f g h i j k l m n o p da eb fc gd he a if b jg c kh d li e mj f nk g ol h pm i n j o k p l m n a b c d e f g h i j k l m n o p g k e 22. a d h b e i c f j d h l f i m g j n h k o i l p j m k n l o m p n o p mycosis fungoides . a c d l .. T / . 448 22 .. gene rearrangement analysis .. Pautrier's microabscess .. TNMB . PUVA narrow band UVB .. CHOP Hodgkin .. 2 S zary S zary syndrome SS. T .. 3 . 22 . S zary S zary syndrome .. 3 T . TNMB T4, B2 . S zary .. 50 . 80 . A T 449. S zary ISCL /EORTC, 2007 . T T N M B. T1 10 A 1 0 0 0,1. T1a T1b . B 2 0 0 0,1. T2 10 . T2a T2b A 1 2 1,2 0 0,1. T3 1 1 cm B 3 0 2 0 0,1. T4 80 . A 4 0 2 0 0.
4 N B 4 0 2 0 1. N0 # A1 1 4 0 2 0 2. N1 NCI LN0-2 . A2 1 4 3 0 0 2. N1a N1b . N2 NCI LN3 B 1 4 0 3 1 0 2. N2a N2b # . N3 NCI LN4 cm . Nx . M NCI . M0 NCI LN0 . M1 NCI LN1 .. B . NCI LN2 3 6 . B0 5 .. B0a B0b . NCI LN3 . B1 5 .. B2 . NCI LN4 . B1a B1b .. B2 S zary 1000 /mL . Olsen E et al. Blood 110 : 1713, 2007 . CHOP .. 22. cm .. S zary CD4 T .. S zary.
