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Pharmacokinetics And Pharmacogenomics Of Tacrolimus
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MEDICATION GUIDELINES FOR SOLID ORGAN TRANSPLANTS
www.transplant.bc.ca13.Tacrolimus 76 14.Valganciclovir 88 15. ... Lea C, Bevan D, Higgins R, Hendry B. The pharmacokinetics of anti-thymocyte globulin (ATG) following intravenous infusion in man. Clin Nephrol. 1996; 45: 29–32. 6. McCune J et al. Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics of Immunosuppressants in Allogeneic Hematopoietic Cell ...
Pharmacokinetics and pharmacogenomics of tacrolimus: a …
www.ildcare.euPharmacokinetics and pharmacogenomics of tacrolimus: a review ⏐ 19 3 Pharmacokinetics 3.1 Genetic factors affecting the pharmacokinetics 3.1.1 Cytochrome P450 (CYP450) 3A4 The CYP3A4 gene is encoded by a 27 kb sequence on chromosome 7q21.3-q22.1 and spans 13 exons117,122,123. CYP3A4 consists of 502 amino acids with a molecular weight