Vaccine Cold Chain

Chapter 16: Pertussis; Epidemiology and Prevention of …

Before the availability of pertussis vaccine in the 1940s, more than 200,000 cases of pertussis were ... cold. The cough gradually becomes more severe and after 1 to 2 weeks, the second, or paroxysmal, stage, begins. ... polymerase chain reaction [PCR], and serology).

  Chain, Cold, Vaccine