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Search results with tag "Assessing drug synergy in combination therapies"
Assessing drug synergy in combination therapies
lincs.hms.harvard.eduNull-hypotheses are based on the observed drug response not a model of mechanism. If “Synergy” means “stronger than my mechanistic model predicts”, then: (1) a genuinely powerful combination isn’t classed as synergistic if it is predictable (2) synergy/antagonism changes as your knowledge and model changes.