Transcription of 1：日本企業の新薬開発力（1） 主要国別オリジン新薬数 …
1 2006 2008 2010 100 . 2012 12 100 1 . IMS World Review, Pharma Projects 1.. Pfizer 7,290. novartis 7,666. Merck 6,773.. 2,819. 1,898. 1,851. 1,251. 4 7,819. annual report (2011) 1$=80 (2011) 2.. (10 ) ( ). 1A .. 2 .. PPAR . Ag . LH-RH . DNA . Ag . HMG-CoAR .. HMG-CoAR .. 3. - . 2001 2012 20 ( 8 . 12 ) . 20 1 ( ATL . CCR4 2012 ) . 19 ( ) . (6000 / ) 80 .. 4.. FDA NME .. Nature Reviews Drug Discovery 11 2010 . Robert Kneller , , , RCAST . 5.. National Institute of Biomedical Innovation .. 3 3 . ( ).. GMP.. , .. HTS , etc . 6.. in vivo .. 7.. ( ) .. CRO.. CMO.. ( ) .. ( ) .. ( ) .. GLP .. GMP .. CMC .. CRO . CMO . 8.
