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1 แนวปฏิบัติการรักษาโรคอุจจาระร่วงเฉียบพลัน

1 5 (1) 5 ..2538 / 2 / / 8 End Decade Goal ..2543 ( ..2000) 5 25% 50% (.)

4 1.1 วิธีการรักษาผ้ป่วยโรคอู ...

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Transcription of 1 แนวปฏิบัติการรักษาโรคอุจจาระร่วงเฉียบพลัน

1 1 5 (1) 5 ..2538 / 2 / / 8 End Decade Goal ..2543 ( ..2000) 5 25% 50% (.)

2 2533 ..1990 ) 1 / / (Household survey) . 2542 1 / / (2) ( Diarrhea ) 3 1 1 1 (3) 2 1.

3 Watery diarrhea non-invasive diarrhea (toxin) cyclic AMP 2 ( hypersecretion ) Vibrio cholera 01, 0139, Enterotoxigenic (ETEC), Enteropathogenic E. coli (EPEC), Staphylococcus, Clostridium perfringens, Vibrio parahemolyticus, Bacillus ceres hypersecretion pH>6, reducing substance <1 +, Na+ >70 / Rotavirus, Norwalk virus, tip villi crypt osmotic diarrhea (osmotic + secretory diarrhea)

4 PH<6 reducing substance >1+ neuromuscular reflex villi 2. Mucus bloody invasive diarrhea lamina propria, cytotoxin Shigella spp, Salmonella spp.

5 , Enteroinvasive (EIEC), Compylobacter jejuni, Yersenia enterolitica, Entamoeba histolytica hemolytic uremic syndrome Shigella dysenteriae 1 EHEC 0157:H7 (4) 1 3 1. (4 -6) ( ) (.)

6 / . ) Na+ K+ Cl- HCO-3 Vibrio cholera 01 Rotavirus 88 53 37 56 30 37 38 25 86 24 22 55 32 18 6 18 120-480 30-90 30-90 30-60 3 1. 2. 3. 1. (7)

7 10 ./ ./ 4 (Oral rehydration therapy-ORT)(3,4) ORT 2.

8 (Prevention of dehydration) 3 - ORT Oral Rehydration Therapy ORS 2 (2 %)

9 4 ( 4 % ) 3- 5 ( 3-5 %) ( % Na 45-90 / ) Na+ 60-90 / K+ 15-25 / Cl 50-80 / HCO- 3 8-12 / 2 % Na+ 90 / , K+ 20 / , Cl- 80 / , HCO- 3 30 / , 111 / ( 2 %) (Self care) ORT ORT ORS ORT10.

10 / . (26) ORT 30-90 ./ ./ ORT . ( Treatment of dehydration ) 2.(4, 9, 10) 5 (deficit) 4- 6 (ORS) 4 maintenance 50.


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