Transcription of 13 多発性硬化症／視神経脊髄炎 - nanbyou.or.jp
1 13 multiple sclerosis MS Neuromyelitis Optica Spectrum Disorders NMOSD NMOSD AQP4 MS NMOSD MS NMOSD AQP4 MS MS Uhthoff NMOSD MS MS AQP4 NMOSD MS MS MS NMOSD
2 MS ADL NMOSD 24 17,073 2014 EDSS II III IV MS A MS a b a VEP
3 MRI b MRI MRI MS T2 MRI MRI T2 24 24 ADEM b B MS a b MRI a (MS T2 b T2 c IgG C MS NMOSD Devic MRI)
4 AQP4 NMOSD NMOSD 2006 Wingerchuk Definite NMOSD Wingerchuk , 2006 MRI MS MRI AQP4 MRI Paty AQP4 Wingerchuk AQP4 NMOSD NMOSD IgG NMOSD MS Bal MRI EDSS EDSS 0 10 Death (MS )
5 A D L 5m 2 3 >500 500m 300m 200m 100m 100m ( ) 100m ( ) E D S S F S FS0 8 7 6 7 6 7 4 ~ 5 5 ~ 6 6 3 7 8 7 8 7 8 7 8 FS0 FS1 * 1 * 2 * FS1 FS2 1 2 3 ~ 4 1 ~ 2 5 FS2 FS3 1 1 2 3 3 FS3 FS4 1 1 ** 2 2 FS4 FS5
6 1 1 FS5 FS6 FS6 * 1 FS ** 5 FS EDSS EDSS EDSS FS EDSS FS 500m EDSS FS FS EDSS FS Functional system FS 0 1 1 2 2 1 2 3 4 3 1 2 3 4 4 1 2 or 2 [grade]
7 3] ( 3 ) 5 1 2 [grade 4] 6 [grade 5] ? ? ? ? ? ? ? ? ? X [grade 3] grade grade II III IV I II III IV I- 20
