2 初回治療（特殊組織型を含む） - jsgo.or.jp

1 39 1988 FIGO 2008 2005 JGOG 1 1 3 70 2 I V 3 I II 2 4 I II 5 7 CQ01 CQ02 CQ14 QOL 8.

2 9 2 40 2 2005 JGOG 1 13 69 10 65 45 31 9,954 30 11 12 14 13 15,16 17.

3 18 CQ03 19 CQ04 isolated tumor cells ITC ITC 200 m ITC pN0 pN0 i pN0 pN1 CQ01 CQ15 41 CQ17 FIGO G1 G2 G3 3 20 serous adenocarcino ma clear cell adenocarcinoma squamous cell carcinoma transitional cell carcinoma, small cell carcinoma.

4 Mixed carcinoma undifferentiated carcinoma I II I II de novo 21 2010 10 1 22 G3 23 2003 24 5 G1 G2 95 86 G3 77 53 63 G3 3 21 13 10 40 10 25 5 45 36 50 10 WHO 2003 I II III IV 43 26 99 IIIc IV 27 13 22 Ia Ib FIGO 25 6 72 1 28 42 2 CQ05 CQ07 CQ13 1 Watanabe Y, Aoki D, Kitagawa R, Takeuchi S, Sagae S, Sakuragi N, et al.

5 Status of surgical treatment procedures for endometrial cancer in Japan results of a Japanese Gynecologic Oncology Group survey. Gynecol Oncol 2007 105 325 328 III 2 Maggino T, Romagnolo C, Zola P, Sartori E, Landoni F, Gadducci A. An analysis of approaches to the treatment of endometrial cancer in western Europe a CTF study. Eur J Cancer 1995 31A 1993 1997 IV 3 DiSaia PJ, Creasman WT. Chapter 3. invasive cervical cancer. In DiSaia PJ, Creasman WT, eds. Clinical Gynecologic Oncology. St. Louis Mosby, 1997 71 74 IV 4 2002 20 416 420 IV 5 II 2002 20 421 427 IV 6 Mariani A, Webb MJ, Keeney GL, Calori G, Podratz KC.

6 Role of wide radical hysterectomy and pelvic lymph node dissection in endometrial cancer with cervical involvement. Gynecol Oncol 2001 83 72 80 III 7 Han CH, Lee KH, Lee HN, Kim CJ, Park TC, Park JS. Does the type of hysterectomy affect the prognosis in clinical stage I endometrial cancer J Obstet Gynaecol Res 2010 36 581 587 III 8 Uterine Neoplasms Version 2. 2012 NCCN Clinical Practice Guidelines in Oncology 9 National Institute for Health and Clinical Excellence IPG239 Laparoscopic techniques for hysterectomy, 2007 http: 10 Naumann RW, Higgins RV, Hall JB. The use of adjuvant radiation therapy by members of the Society of Gynecologic Oncologists. Gynecol Oncol 1999 75 4 9 IV 11 Partridge EE, Jessup JM, Donaldson ES, Taylor PT, Randall M, Braley P, et al.

7 1,996 patients care evaluation study PCF of cancer of the corpus uteri, National Cancer Database NCDB American College of Surgery. Gynecol Oncol 1999 72 445 IV 12 Amadori A, Bucchi L, Gori G, Falcini F, Saragoni L, Amadori D. Frequency and determinants of lymphadenectomy in endometrial carcinoma a population based study from northern Italy. Ann Surg Oncol 2001 8 723 738 III 13 Crawford SC, DeCaestecker L, Gillis CR, Hole D, Davis JA, Penney G, et al. Staging quality is related to the survival of women with endometrial cancer a Sccottish population based study. Deficient surgical staging and omission of adjuvant radiotherapy is associated with poorer survival of women diagnosed with endometrial cancer in Scotland during 1996 and 1997.

8 Br J Cancer 2002 86 1837 1842 III 14 Creutzberg CL, van Putten WL, Koper PC, Lybeert ML, Jobsen JJ, W rl m Rodenhuis CC, et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage I endome trial carcinoma multicentre randomized trial. PORTEC study group. post operative radiation therapy in endometrial carcinoma. Lancet 2000 355 1404 1411 II 15 Chan JK, Urban R, Cheung MK, Shin JY, Husain A, Teng NN, et al. Lymphadenectomy in endometrioid uterine cancer staging how many lymph nodes are enough a study of 11,443 patients. Cancer 2007 109 2454 2460 III 16 Chan JK, Cheung MK, Huh WK, Osann K, Husain A, Teng NN, et al. Therapeutic role of lymph node resection in endometrioid corpus cancer a study of 12,333 patients.

9 Cancer 2006 107 1823 1830 III 43 17 ASTEC study group, Kitchener H, Swart AM, Qian Q, Amos C, Parmar MK. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer MRC ASTEC trial a randomised study. Lancet 2009 373 125 136 II 18 Benedetti Panici P, Basile S, Maneschi F, Alberto Lissoni A, Signorelli M, Scambia G, et al. Systematic pelvic lymphadenectomy vs no lymphadenectomy in early stage endometrial carcinoma randomized clinical trial. J Natl Cancer Inst 2008 100 1707 1716 II 19 Todo Y, Kato H, Kaneuchi M, Watari H, Takeda M, Sakuragi N. Survival effect of para aortic lymphadenectomy in endometrial cancer SEPAL study a retrospective cohort analysis.

10 Lancet 2010 375 1165 1172 III 20 3 2012 21 2007 62 69 IV 22 2010 2012 64 1029 1077 IV 23 Rose PG. Endometrial carcinoma. New Engl J Med 1996 335 640 649 IV 24 51 2012 64 1078 1141 III 25 Soslow RA, Bissonnette JP, Wilton A, Ferguson SE, Alektiar KM, Duska LR, et al. Clinicopathologic analysis of 187 high grade endometrial carcinomas of different histologic subtypes similar outcomes belie distinctive biologic differences. Am J Surg Pathol 2007 31 979 987 III 26 Memarzadeh S, Holschneider CH, Bristow RE, Jones NL, Fu YS, Karlan BY, et al.