血尿診断ガイドライン2013 - jspn.jp

1 2013.. V.. 191 367 . CQ17 . 3 .. Ca . TBMD IgA . B .. 1. a) 2004 06. 3 .. IgA .. Wilms 3) .. 2.. 1974 .. 1980 . 70 4.. 2000 30 1) 1 . * .. 1) . 1975 10 22 Ca . 103 8 TBMD IgA . 1985 10 21 Wilms . 124 1 . 2) 3 1 4 1 .. IgA 4,5) .. Alport 6) . nutcracker phenomenon /. nutcracker syndrome .. 3.. 2007 2 .. 192 368 . 34. V .. 7,8) .. Ca .. 37 Ca . 64 Ca b) PubMed . Japanese, child 6 12 years, adolescent 13 18 years, incidence, frequency, cause, ethiology, microscopic . hematuria[majr] . 6 12 13 18 1990 9 . 2011 .. 1) . 2004; 63: 365 70.. 2) .. 2000; 13: 113 7.

2 3) . 2009; 21: 209. 4) Schr der CH, Bontemps CM, Assmann KJ, Schuurmans Stekhoven . JH, Foidart JM, Monnens LA, Veerkamp JH. Renal biopsy and fam- .. IgA . ANCA .. Alport .. Ca .. (11,21 BK . Wilms .. 193 369 . 35. ily studies in 65 children with isolated hematuria. Acta Paediatr Scand.. 2000; 104: 30 5. 1990; 79: 630 6. 8) Mazzoni MB, Kottanatu L, Simonetti GD, Ragazzi M, Bianchetti MG, 5) Piqueras AI, White RH, Raafat F, Moghal N, Milford DV. Renal bi- Fossali EF, Milani GP. Renal vein obstruction and orthostatic protein- opsy diagnosis in children presenting with haematuria.

3 Pediatr Nephrol. uria: a review. Nephrol Dial Transplant. 2011; 26: 562 5.. 1998; 12: 386 91. 6) Carasi C, Van t Hoff WG, Rees L, Risdon RA, Trompeter RS, Dillon a) . MJ. Childhood thin GBM disease: review of 22 children with family 2009 . studies and long-term follow up. Pediatr Nephrol. 2005; 20: 1098 105. b) . 7) . 1985 ; 133 : 387 8.. CQ18 ? . 1 3 . 1 1 2 1 . C1 .. 1 3 . 1 1 2 . 1 1 . 30 . 5 1 1,2) .. 1 .. CQ19 .. 1 .. 30 .. 194 370 . 36. V .. PubMed 1) .. 1983; 87: 808 16. Japanese, child 6 12 years, adolescent 13 18 years, 2) . referral, consultation, physician s role, observation.

4 1999; 103: 543 8. kidney biopsy, diagnosis, microscopic, hematuria, .. 6 12 13 18 1990 9 . 2011 . CQ19 ? . B .. B . Ca Ca/Cr 7 5 7 3 5 1 3 . 12 24 Ca . 4 mg/kg/ . 1 TP/ 2 . Cr 2 2 pH . 1 .. 1 . IgA Alport . Alport . Alport . Alport . ANCA . B C .. Ca .. D Ca . Ca .. 195 371 . 37. 2 Cr . 12 Cr mg/dL . 50 . 3 5 6 8 9 11 1 2 3 4 5 6 7 8 9 10 11 12 16 Cr mg/dL . 50 . 12 13 14 15 12 16 Cr mg/dL . 50 . 12 13 14 15 Ca / . 1+ 6 12 . 2+ 3 6 . 3+ 1 3 . CRP ASO IgG IgA CH50 4+ 2 . C3 . ANCA . dsDNA ANCA B C Alb g/dL . IgA . IgA 2 . 3 Cr .. 1) . 38. 196 372.

5 V . 3 50 .. 90th 95th 99th 90th 95th 99th 1 99/52 103/56 110/64 100/54 104/58 111/65. 2 102/57 106/61 113/69 101/59 105/63 112/70. 3 105/61 109/65 116/73 103/63 107/67 114/74. 4 107/65 111/69 118/77 104/66 108/70 115/77. 5 108/68 112/72 120/80 106/68 110/72 117/79. 6 110/70 114/74 121/82 108/70 111/74 119/81. 7 111/72 115/76 122/84 109/71 113/75 120/82. 8 112/73 116/78 123/86 111/72 115/76 122/83. 9 114/75 118/79 125/87 113/73 117/77 124/84. 10 115/75 119/80 127/88 115/74 119/78 126/86. 11 117/76 121/80 129/88 117/75 121/79 128/87. 12 120/76 123/81 131/89 119/76 123/80 130/88.

6 13 122/77 126/81 133/89 121/77 124/81 132/89. 14 125/78 128/82 136/90 122/78 126/82 133/90. 15 127/79 131/83 138/91 123/79 127/83 134/91. 16 130/80 134/84 141/92 124/80 128/84 135/91. 17 132/82 136/87 143/94 125/80 129/84 136/91.. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004; 114: 555 76.. PubMed . Japanese, child 6 12 years, adolescent 13 18 years, referral, consultation, physician s role, observation, kidney biopsy, diagnosis, microscopic, hematuria.

7 CT . 6 12 13 18 1990 9 . 2011 . CT . 1) Uemura O, Honda M, Matsuyama T, Ishikura K, Hataya H, Yata N, Nagai T, Ikezumi Y, Fujita N, Ito S, Iijima K, Kitagawa T. Age, gender, . and body length effects on reference serum creatinine levels determined by an enzymatic method in Japanese children: a multicenter study. Clin Exp Nephrol. 2011; 15: 694 9. 2) 2) .. 2000; 104: 30 5. 3) 3) Shin JI, Park JM, Lee JS, Kim MJ. Doppler ultrasonographic indices in diagnosing nutcracker syndrome in children. Pediatr Nephrol. 2007; 22: 409 13.. X . CT . 197 373 . 39. CQ20 ?

8 CT B . Wilms . B .. Wilms 100. CT .. CT PubMed . Japanese, child 6 12 years, adolescent 13 18 years, Wilms neoplasms, diagnosis, diggerential, diagnosis, micro . Wilms 18 scopic, hematuria, 6 12 . 24 13 18 1990 9 2011 .. Wilms 40 . Wilms 7 Wilms 1) . Wilms . WT1 Denys Drash .. Beckwith Wiedemann WAGR . 2000; 104: 961 7. Sotos . von Recklinghausen .. 1) 20 . CQ21 ? . C2 .. QOL .. 1 CKD .. 40. 198 374 . V .. 23 PubMed . a) 1 Japanese, child 6 12 years, adolescent 13 18 years, exercise, sports, diggerential, diet, food, hematuria, 6 12 . 13 18 1990 9 2011.

9 A) 23 . 1 .. A.. B.. 1) . C. 3 .. D. 3 . 3) 2 . 4) 1 5 .. 2 . E.. 6) 2 . 7) 1 .. 1) . 2) D . 3) . 4) . 5) 2 1 2 . 6) . 7 .. 199 375 . 41.