2017 Hypertension Guideline Data Supplements

1 2017 Hypertension Guideline data Supplements 2017 Hypertension Guideline data Supplements (Section numbers correspond to the full-text Guideline .). Table of Contents data supplement 1. Coexistence of Hypertension and Related Chronic Conditions (Section ) .. 7. data supplement 2. Definition of High BP (Section ).. 8. data supplement 3. Out-of-Office and Self-Monitoring of BP (Section ) .. 18. data supplement 4. White Coat Hypertension (Section ) .. 21. data supplement 5. White Coat Hypertension (Prevalence) (Section ) .. 23. data supplement 6. White Coat Hypertension (Correlation with Clinical Outcomes) (Section ) .. 25. data supplement 7. Renal Artery Stenosis (Section ) .. 27. data supplement 8. RCTs Comparing Obstructive Sleep Apnea (Section ) .. 29. data supplement 9. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Dietary Fiber Intake) (Section ) .. 31. data supplement 10. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Fish Oil) (Section ).

2 33. data supplement 11. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Potassium Supplementation to Placebo or Usual Diet) (Section ) .. 34. data supplement 12. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Protein Intake on BP) (Section ).. 36. data supplement 13. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Sodium Reduction to Placebo or Usual Diet) (Section ) .. 38. data supplement 14. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Stress Reduction) (Section ) .. 43. data supplement 15. RCTs and Meta-analyses Studying the Effect of Nonpharmacologic Interventions on BP (Dietary Patterns) (Section ) .. 44. data supplement 16. RCTs and Meta-analysis RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Alcohol Reduction) (Section ) .. 51. data supplement 17. RCTs and Meta-analysis RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Calcium Supplementation) (Section ).

3 55. data supplement 18. RCTs and Meta-analyses RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Physical Activity) (Section ) .. 56. 2017 American College of Cardiology Foundation and American Heart Association, Inc. 1. 2017 Hypertension Guideline data Supplements data supplement 19. RCTs and Meta-analysis RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Magnesium Supplementation) (Section ) .. 59. data supplement 20. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Weight Loss) (Section ) .. 61. data supplement 21. RCTs and Systematic Reviews for RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Section ) .. 64. data supplement 22. Observational Studies of CV Target Organ Damage Including LVH (Section ) .. 66. data supplement 23. RCTs on Use of Risk Estimation to Guide Treatment of Hypertension (Section ) .. 67. data supplement 24. Follow-Up After Initial BP Evaluation (Section ).

4 81. data supplement 25. RCTs for General Principles of Drug Therapy (Combination Therapies that Inhibit the RAAS) (Section ) .. 83. data supplement 26. BP Goal for Patients with Hypertension (Section ).. 85. data supplement 27. Choice of Initial Medication (Section ) .. 92. data supplement 28. Follow-Up After Initiating Antihypertensive Drug Therapy (Section ) .. 95. data supplement 29. Monitoring Strategies to Improve Control of BP in Patients on Drug Therapy for High BP (Section ) .. 97. data supplement 30. RCTs Comparing Stable Ischemic Heart Disease (Section ) .. 100. data supplement 31. Meta-analyses of ischemic heart disease (Section ) .. 110. data supplement 32. Nonrandomized Trials, Observational Studies, and/or Registries of Ischemic Heart Disease (Section ) .. 111. data supplement 33. RCTs Comparing Heart Failure (Section ) .. 112. data supplement 34. RCTs Comparing HFrEF (Section ) .. 113. data supplement 35.

5 RCTs Comparing HFpEF (Section ).. 119. data supplement 36. Nonrandomized Trials, Observational Studies, and/or Registries of HFpEF (Section ) .. 122. data supplement 37. RCTs Comparing CKD (Section ) .. 123. data supplement 38. Nonrandomized Trials, Observational Studies, and/or Registries of CKD (Section ).. 133. data supplement 39. RCTs Comparing Hypertension after Renal Transplantation (Section ) .. 137. data supplement 40. Nonrandomized Trials, Observational Studies, and/or Registries for Hypertension after Renal Transplantation (Section ) .. 140. data supplement 41. RCTs Comparing Acute Intracerebral Hemorrhage Outcomes (Section ) .. 143. data supplement 42. RCTs Comparing Acute Ischemic Stroke Outcomes (Section ) .. 147. data supplement 43. RCTs Comparing Secondary Stroke Prevention (Section ) .. 158. data supplement 44. Nonrandomized Trials, Observational Studies, and/or Registries of Secondary Stroke Prevention (Section ).

6 161. 2017 American College of Cardiology Foundation and American Heart Association, Inc. 2. 2017 Hypertension Guideline data Supplements data supplement 45. RCTs and Meta-analysis Comparing PAD (Section ) .. 168. data supplement 46. RCTs and Meta-analyses Comparing BP Targets in DM (Section ) .. 174. data supplement 47. Nonrandomized Trials, Observational Studies, and/or Registries in DM (Section ) .. 183. data supplement 48. Atrial Fibrillation (Section ) .. 190. data supplement 49. Valvular Heart Disease (Section ) .. 191. data supplement 50. RCTs and Meta-analysis Comparing Valvular Heart Disease (Section ) .. 194. data supplement 51. RCTs Comparing Race/Ethnicity (Section ) .. 197. data supplement 52. RCTs Comparing Women With Hypertension (Section ) .. 201. data supplement 53. RCTs Comparing Pregnancy (Section ) .. 203. data supplement 54. RCT for Older Persons (Section ) .. 204. data supplement 55. RCTs Comparing Hypertensive Crises and Emergencies (Section ).

7 204. data supplement 56. RCTs Assessing Impact of Hypertension Therapy on Dementia Incidence (Section ) .. 207. data supplement 57. RCTs for Patients Undergoing Surgical Procedures (Section ) .. 210. data supplement 58. Observational and Nonrandomized Studies for Patients Undergoing Surgical Procedures (Section ) .. 211. data supplement 59. RCTs of Adherence and Compliance with Fixed Dose Combinations Regimens (Section ) .. 213. data supplement 60. Nonrandomized Trials, Observational Studies, and/or Registries of Antihypertensive Medication Adherence Strategies (Section ).. 214. data supplement 61. RCTs and Meta-analysis on Strategies to Promote Lifestyle Modification (Section ) .. 220. data supplement 62. RCTs, Meta-analyses, and Systematic Reviews on the Effect of Structured, Team-based Care Interventions for Hypertension Control (Section ).. 221. data supplement 63. Electronic Health Records and Patient Registries (Section ).

8 227. data supplement 64. RCTs, Meta-analyses, and Systematic Reviews on the Effect of Telehealth Interventions to Improve Hypertension Control (Section ).. 232. data supplement 65. RCTs and Observational Studies that Report on the Effect of Performance Measures and on Hypertension Control (Section ) .. 236. data supplement 66. RCTs, Meta-analyses, and Systematic Reviews on Quality Improvement Strategies on Hypertension Treatment Outcomes (Section ) .. 238. data supplement 67. Nonrandomized Trials, Observational Studies, and/or Registries of Effect of Quality Improvement Strategies on Hypertension Treatment Outcomes (Section ) .. 244. data supplement 68. RCTs Comparing Financial Incentives (Section ) .. 245. Additional data supplement Tables and 252. 2017 American College of Cardiology Foundation and American Heart Association, Inc. 3. 2017 Hypertension Guideline data Supplements data supplement A. Treatment of HFrEF Stages C and D.

9 252. data supplement B. Medication Adherence Assessment Scales .. 253. data supplement C. Categories Defining Normal BP, Elevated BP, and Stages 1, 2, and 3 Hypertension .. 253. data supplement D. Fixed-Dose Combination Antihypertensive Drugs .. 255. data supplement E. Examples of Hypertension Quality Improvement Strategies .. 256. data supplement F. Barriers and Improvement Strategies in Antihypertensive Medication Adherence (350-354) .. 257. data supplement G. Examples of Strategies to Promote Lifestyle Modification Interventions in Patients With Hypertension (319,320,356-362).. 258. data supplement H. Responsibilities and Roles of the Hypertension 259. data supplement I. Examples of Telehealth Strategies and Technologies to Promote Effective Hypertension Management .. 260. data supplement J. Publicly Available Performance Measures Used to Assess Hypertension Care Quality Services (364-368) .. 261. data supplement K.

10 Online Quality Improvement Resources for Treatment and Control of Hypertension .. 263. 264. Search Terms: An extensive evidence review, which included literature derived from research involving human subjects, published in English, and indexed in MEDLINE. (through PubMed), EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and other selected databases relevant to this Guideline , was conducted between February and August 2015. Key search words included but were not limited to the following: adherence; aerobic; alcohol intake;. ambulatory care; antihypertensive: agents, drug, medication, therapy; beta adrenergic blockers; blood pressure: arterial, control, determination, devises, goal, high, improve, measurement, monitoring, ambulatory; calcium channel blockers; diet; diuretic agent; drug therapy; heart failure: diastolic, systolic;. Hypertension : white coat, masked, ambulatory, isolated ambulatory, isolated clinic, diagnosis, reverse white coat, prevention, therapy, treatment, control.