2017 Hypertension Guideline Data Supplements

1 2017 Hypertension Guideline Data Supplements 2017 Hypertension Guideline Data Supplements (Section numbers correspond to the full-text Guideline .). Table of Contents Data Supplement 1. Coexistence of Hypertension and Related Chronic Conditions (Section ) .. 7. Data Supplement 2. Definition of High BP (Section ).. 8. Data Supplement 3. Out-of-Office and Self-Monitoring of BP (Section ) .. 18. Data Supplement 4. White Coat Hypertension (Section ) .. 21. Data Supplement 5. White Coat Hypertension (Prevalence) (Section ).

2 23. Data Supplement 6. White Coat Hypertension (Correlation with Clinical Outcomes) (Section ) .. 25. Data Supplement 7. Renal Artery Stenosis (Section ) .. 27. Data Supplement 8. RCTs Comparing Obstructive Sleep Apnea (Section ) .. 29. Data Supplement 9. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Dietary Fiber Intake) (Section ) .. 31. Data Supplement 10. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Fish Oil) (Section ) .. 33. Data Supplement 11. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Potassium Supplementation to Placebo or Usual Diet) (Section ).

3 34. Data Supplement 12. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Protein Intake on BP) (Section ).. 36. Data Supplement 13. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Sodium Reduction to Placebo or Usual Diet) (Section ) .. 38. Data Supplement 14. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Stress Reduction) (Section ) .. 43. Data Supplement 15. RCTs and Meta-analyses Studying the Effect of Nonpharmacologic Interventions on BP (Dietary Patterns) (Section ).

4 44. Data Supplement 16. RCTs and Meta-analysis RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Alcohol Reduction) (Section ) .. 51. Data Supplement 17. RCTs and Meta-analysis RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Calcium Supplementation) (Section ) .. 55. Data Supplement 18. RCTs and Meta-analyses RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Physical Activity) (Section ) .. 56. 2017 American College of Cardiology Foundation and American Heart Association, Inc.

5 1. 2017 Hypertension Guideline Data Supplements Data Supplement 19. RCTs and Meta-analysis RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Magnesium Supplementation) (Section ) .. 59. Data Supplement 20. RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Weight Loss) (Section ) .. 61. Data Supplement 21. RCTs and Systematic Reviews for RCTs Studying the Effect of Nonpharmacologic Interventions on BP (Section ) .. 64. Data Supplement 22. Observational Studies of CV Target Organ Damage Including LVH (Section ).

6 66. Data Supplement 23. RCTs on Use of Risk Estimation to Guide Treatment of Hypertension (Section ) .. 67. Data Supplement 24. Follow-Up After Initial BP Evaluation (Section ) .. 81. Data Supplement 25. RCTs for General Principles of Drug Therapy (Combination Therapies that Inhibit the RAAS) (Section ) .. 83. Data Supplement 26. BP Goal for Patients with Hypertension (Section ).. 85. Data Supplement 27. Choice of Initial Medication (Section ) .. 92. Data Supplement 28. Follow-Up After Initiating Antihypertensive Drug Therapy (Section ).

7 95. Data Supplement 29. Monitoring Strategies to Improve Control of BP in Patients on Drug Therapy for High BP (Section ) .. 97. Data Supplement 30. RCTs Comparing Stable Ischemic Heart Disease (Section ) .. 100. Data Supplement 31. Meta-analyses of ischemic heart disease (Section ) .. 110. Data Supplement 32. Nonrandomized Trials, Observational Studies, and/or Registries of Ischemic Heart Disease (Section ) .. 111. Data Supplement 33. RCTs Comparing Heart Failure (Section ) .. 112. Data Supplement 34.

8 RCTs Comparing HFrEF (Section ) .. 113. Data Supplement 35. RCTs Comparing HFpEF (Section ).. 119. Data Supplement 36. Nonrandomized Trials, Observational Studies, and/or Registries of HFpEF (Section ) .. 122. Data Supplement 37. RCTs Comparing CKD (Section ) .. 123. Data Supplement 38. Nonrandomized Trials, Observational Studies, and/or Registries of CKD (Section ).. 133. Data Supplement 39. RCTs Comparing Hypertension after Renal Transplantation (Section ) .. 137. Data Supplement 40. Nonrandomized Trials, Observational Studies, and/or Registries for Hypertension after Renal Transplantation (Section ).

9 140. Data Supplement 41. RCTs Comparing Acute Intracerebral Hemorrhage Outcomes (Section ) .. 143. Data Supplement 42. RCTs Comparing Acute Ischemic Stroke Outcomes (Section ) .. 147. Data Supplement 43. RCTs Comparing Secondary Stroke Prevention (Section ) .. 158. Data Supplement 44. Nonrandomized Trials, Observational Studies, and/or Registries of Secondary Stroke Prevention (Section ) .. 161. 2017 American College of Cardiology Foundation and American Heart Association, Inc. 2. 2017 Hypertension Guideline Data Supplements Data Supplement 45.

10 RCTs and Meta-analysis Comparing PAD (Section ) .. 168. Data Supplement 46. RCTs and Meta-analyses Comparing BP Targets in DM (Section ) .. 174. Data Supplement 47. Nonrandomized Trials, Observational Studies, and/or Registries in DM (Section ) .. 183. Data Supplement 48. Atrial Fibrillation (Section ) .. 190. Data Supplement 49. Valvular Heart Disease (Section ) .. 191. Data Supplement 50. RCTs and Meta-analysis Comparing Valvular Heart Disease (Section ) .. 194. Data Supplement 51. RCTs Comparing Race/Ethnicity (Section ).