5008 Therapy System - fmc-au.com

1 Haemodialysis5008 Therapy SystemThe 5008 Therapy SystemAVision turned into RealityThe 5008 therapy system was developed to fulfil currentchallenges in haemodialysis: continually increasing patientnumbers with a growing share of medically challengingpatients, combined with often limited funding and 5008 therapy system therefore offers a combinationof convincingly easy handling with a thoughtful use of thedialysis-relevant resources, coupled with the highesttreatment quality and patient safety. The serial configuration of the 5008 Therapy Systemoffers unique therapeutic possibilities: ONLINE Haemodiafiltration currently the most efficient renal replacement Therapy OCM Online Clearance Monitoring and plasma sodium measurement Ultrapure dialysis fluid (DIASAFE plus) Na- and UF-profilesTouching Experience Single-Needle treatment Integrated heparin pump, bibag -connector and arterial clamp Highly automated procedures.

2 - Online priming, bolus and reinfusion completelywithout using saline rinse solutions in either bags or bottles- AutoFlow, EcoFlow savings of water, energy and dialysate- AutoSub adjustment of optimum HDF-substitution-rate Innovative user-guidance via a central, freely rota-tabletouchscreen monitor Sophisticated data management easy data input anddocumentation; alternatively, with PatientCard (offline) or via net-workintegration (online)These fully integrated functions, together with the easy,intuitive operation of the 5008 therapy system , allowthe delivery of a superior Therapy quality together withan optimal use of the human, medical and technicalresources innovative therapeutic tools and options (e.)

3 An effective blood pressure management) are avail-able fully integrated with convenient operation via the5008 touchscreen: Blood Pressure Monitor (BPM) Blood Temperature Monitor (BTM) Blood Volume Monitor (BVM) Data management System Finesse or TDMS/dXp( Therapy -Data-Management- System / Data exchange function)5008 A Touching ExperienceCardioprotective Haemodialysiswith the 5008 therapy system Despite significant improvements in the quality andefficacy of haemodialysis Therapy in recent years, cardio-vascular disease still remains the leading cause of deathfor dialysis patients. The newly developed 5008 TherapySystem allows to effectively minimise dialysis-relatedfactors that may influence cardiovascular disease inthe dialysis 5008 therapy system enables, for the first time, amore general application of state-of-the-art ONLINEH aemodiafiltration as it perfectly balances best thera-py with optimised practicability and an efficient use of , because of its high flexibility, the 5008 therapy system is best prepared to adapt the dialysistherapy according to the individual needs of thepatient.

4 At the same time, numerous integrated safetysystems guarantee utmost patient Therapy for your PatientsONLINE Haemodiafiltration The Therapy of ChoiceONLINE Haemodiafiltration, with its numerous positive effects on uraemia-relatedcardiovascular risk factors, is currently acknowledged as the most effective dialysistreatment modality that comes closest to the elimination profile of the natural kidney. The results of two recent studies demonstrate that patients treated with ONLINEHDF had a significant 35 % reduction of mortality risk compared to patients treatedwith standard haemodialysis (Jirka et al.(1)and Canaud et al.(2))Furthermore, convective therapies reduce dialysis-associated side-effects andintradialytic symptoms compared to standard haemodialysis (Altieri et al.)

5 (3))These clinical benefits of ONLINE HDF Therapy are attributed to the more effec-tive elimination of a broader spectrum of uraemic toxins, combined with minimalstimulation of inflammation and oxidative Achieving Cardioprotective HaemodialysisHaemodiafiltration Reduces Mortality and Morbidity1. Jirka T, Cesare S, Di Benedetto A et al.: The impact of online HDF on patient survival: Results from a large network database. Nephrol Dial Transplant 2005; 20 (Suppl 5): B, Bragg-Gresham J, Marshall MR et al: Mortality risk for patients receiving hemodiafiltration versus hemodialysis: Europeanresults from the DOPPS. Kidney Int 2006; 69: P, Sorba GB, Bolasco PG et al.: Online predilution hemofiltration versus ultrapure high-flux haemodialysis, a multicentre prospective study in 23 patients.

6 Blood Purif 1997; 15: 169-181 Patient Surveillance SystemsPatient Safety and Minimisation of Undesirable IncidencesBlood Temperature Monitor BTM: Effective haemodynamic stabilisationand recirculation measurement Self-evident programme settingsminimise operational errors Breakthrough technology safety sys-tems e. g. various leakage sensors(at the extracorporeal blood circuit,the DIASAFE plus-filters and thehydraulics)Deaths(%)Deaths/100patient years424143 ONLINE HFHigh-Flux HD%ofpatientsshowingatleast1episodepermo nth61393026112443317413591117499 Hypotension Arrhythmia Muscular Pruritus VomitingHypertension Dypnea cramps Headache NauseaofUndesirable Incidences Emergency-button for quick res-ponse in case of emergencies Consistent pre-setting of patient-spe-cific treatment parameters.

7 Offline withPatientCard or online via LAN networkconnection (Finesse or TDMS/dXp) Non-invasive, air-free arterial pres-sure monitoring Clearly-structured, door-securedextracorporeal blood moduleOnline Clearance Monitor OCM :Reliable measurement and analysis of dialysisefficiency and dialysis dose (Kt/V) plus continuous monitoring of plasma sodiumconcentrationBlood Volume Monitor BVM:Controlled ultrafiltration for effective fluidremoval with less incidence of hypo-tensive episodesBlood Pressure Monitor BPM: Fully automated and non-invasive bloodpressure monitoring (systolic & diastolicblood pressure, MAP, pulse) Best HandlingTailor-made to Meet the Needs of all OperatorsThe 5008 therapy system is the first haemodialysis System created out of the practice for the practice that is, created by users for users!

8 The complete 5008 operation procedure was designed in aneasy and ergonomic way in order to give the nursing personnel much-needed time for patient care. Well-designed User Interface Navigation System Large (15'' TFT), individually adjustable and freely rotatable touchscreen monitor 3-D buttons with feedback Intuitively correct user-guidance phil-osophy: designed for quick, error-freedata entry5008 Experience the DifferenceEasy, Rapid and Safe Data Management Patient and Therapy data of currentand previous three treatments isalways available Individualised Therapy prescriptionand documentation: Offline with PatientCard Online via an integrated LAN net-work connector (Data managementsystem Finesse or Therapy -Data-Management- System TDMS/DataExchange function dXp)Unmatched Service-Friendliness Comprehensive service programand technical error memory(accesswith ServiceCard ) Long-living components with inno-vative fixation( Snap-lock technology) Real-time hydraulic flow charts(accessible also during the Therapy )

9 Convenient accessibility to all partsand componentsOptimised ErgonomicsEfficient and SustainableWith the 5008 therapy system , Fresenius Medical Care offers a System to per-form premium dialysis Therapy that at the same time supports the sensible andsustainable use of the limited resources available. Optimised 5008 bibag : rapid andhygienic one-hand connection Optimised 5008 bloodline System :easy, machine-assisted set-up &dismantling Workflow optimisation by highlyautomated user assistance:- Multiple automated tests during preparation-ONLINE priming, bolus and blood reinfusion- Self-initiating functions (e. g. UF, OCM ,ONLINE HDF and heparinisation)- Numerous auto-regulating mechanisms(e. g. AutoFlow, EcoFlow, AutoSub, AutoSN)-Automated disinfection programONLINE plus- System Ultrapure and Physiologic Rinse-and Substitution-Solutions ONLINE HDF, ONLINE Priming, ON-LINE Bolus and ONLINE Reinfusion.

10 -Complete substitution of all conventionalsaline rinse-solutions and substitution-solutions (bags or bottles) with ONLINE prepared electrolyte solutions highly physiological having patient-individual compositions Optimised workflow for all operators and users Prepared for Future Therapy -, Monitoring- and Safety-Modules thanks tothe well-proven modular design, roomy installation space plus free processor-and memory The Sustainable Haemodialysis Therapy SystemOptimal Use of Resources withPremium Therapy Standard AutoFlow Automatic adjust-ment and optimal adaptation ofdialysate flow to effective bloodflow. Allows substantial savingsof water, concentrates and energywhile maintaining a constant dia-lysis quality.