第69回日本産科婦人科学会 ... - jsog.umin.ac.jp

1 06 69 2017 4 13 69 STI Treponema pallidum Neisseria gonorrhoeae Haemophilus ducreyi Calymmatobacterium granulomatis Gardnerella vaginalis Group B Streptococcus Shigella Salmonella Campilobacter Ureaplasma urealyticum Mycoplasma hominis Chlamydia trachomatis (L1 3) Chlamydia trachomatis (B K) 2007 4 1 HIV/AIDS S S Y O N H F S K 23 13 10 1 1 1 15

2 90 91 15 05,00010,00015,00020,00025,00030,00015-1 920-2425-2930-3435-3940-4445-4950-5455-5 960-6465+ STD STD STD STD 2012 2012 2013 2013 113,943 111,095 121,875 104,748 STI ( ) Fitz-Hugh-Curtis syndrome SEX PID Evidence for Long-Term Cervical Persistence of Chlamydia trachomatis by omp1 Genotyping Deborah Dean, et al.

3 The Journal of Infectious Diseases 2000;182:909 16 0500010000150002000025000300003500040000 4500019992000200120022003200420052006200 720082009201020112012201320142015 EIA DNA DNA EIA SDA TMA PCR 2016 2016 11 1 CDC 2015 Sexually Transmitted Diseases Treatment Guidelines 2016 WHO treatment guidelines Neisseria gonorrhoeae 1 30 02,0004,0006,0008,00010,00012,00014,0001 6,00018,00020,000 TMA 80 30 50 2016 11 1 2014 12 22 CTRX 1 31 , No1 2010 MIC g/ml) H41 PBP2 X X Case report of Ceftriaxone resistant Neisseria gonorrhoeae was presented in Annual meeting of Japanese Society for STI, December 2009.

4 Ceftriaxone-resistant strains H041 (Japan) F89 (France, Spain) A8806 (Australia) GU140106 (Japan) 21 2000 21 3 3 3 2 1 9 5 3 4 2013 66 1923 1929 ( ) 18 01000200030004000500060007000 2005 1999 2 20 30 3 8 3 25% 2011: 2011 22 1 Suppl 70-3 5- Sinecatechins 2 1 2 4 20 40 HPV6 11 2 2 2 2-4 RRP Image reprinted with permission from Glikman D.

5 , et Engl J Med 2005; 352:e22. Copyright 2005 Massachusetts Medical Society. All rights reserved. CS. Laryngoscope. 2001;111:57 69. 2. Abramson AL, Nouri M, Mullooly V, Fisch G, Steinberg BM. J Med Virol. 2004;72:473 477. BM, DiLorenzo TP. Cancer Metastasis Rev. 1996;15:91 112. 4. Szentirmay Z, P lus K, Tam s L, et al. Cancer and Metastasis Reviews. 2005;24:19 34. 5. Derkay CS, Darrow DH. Ann Otol Rhinol Laryngol. 2006;115:1-11. gold standard) PCR LAMP 20~30% (15 (2~7 ) HSV 200mg 5T 5 5 10 500mg)2T 2 5 10 (250mg)3T 3 5 5mg/kg/ 8 7 500mg)1T 1 1 20 HPV sexual activity 1) WHO GUIDELINES FOR THE Treatment of Chlamydia trachomatis (Guideline) 2017 4 10 2)

6 Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC): Sexually transmitted diseases treatment guidelines, 2015, Chlamydial infections. MMWR Recomm Rep 2015; 64: 55-60 PMID: 26042815 (Guideline) 3) JAID/JSC 2014 2014 234-236 (Guideline) 4) 2016 2016 11 1 (Guideline) 2017 4 10 5) III . pp119-182 2012