ABIM Laboratory Test Reference Ranges January 2022

1 Laboratory TestsReference Ranges1,25-Dihydroxyvitamin D (1,25-dihydroxycholecalciferol), serum See Vitamin D metabolites17-Hydroxyprogesterone, serum Female, follicular 80 ng/dL Female, luteal 285 ng/dL Female, postmenopausal 51 ng/dL Male (adult) 220 ng/dL 25-Hydroxyvitamin D (25-Hydroxycholecalciferol), serum See Vitamin D metabolites5-Hydroxyindoleacetic acid, urine2 9 mg/24 hr6-Thioguanine, whole blood230 400 pmol/8x108 RBCsAbsolute neutrophil count (ANC)2000 8250/ LAcid phosphatase, serum (Bodansky) units/mL Prostatic unit/mLACTH, plasma10 60 pg/mL Activated partial thromboplastin time25 35 secondsADAMTS13 activity>60%Adrenocorticotropic hormone (ACTH), plasma 10 60 pg/mL Albumin, g/dLAlbumin, urine 25 mg/24 hrAlbumin-to-creatinine ratio, urine 30 mg/gAldolase, IU/mLAldosterone, plasma Supine or seated 10 ng/dL Standing 21 ng/dL Low-sodium diet (supine) 30 ng/dLAldosterone, urine5 19 g/24 hrAlkaline phosphatase, serum30 120 U/LAlkaline phosphatase, bone g/L for premenopausal womenAlpha1-antitrypsin (AAT)

2 , serum150 350 mg/dLAlpha2-antiplasmin activity, plasma75% 115%Alpha-amino nitrogen, urine100 290 mg/24 hrAlpha-fetoprotein, serum 10 ng/mLAmino acids, urine200 400 mg/24 hrAminotransferase, serum alanine (ALT, SGPT)10 40 U/LAminotransferase, serum aspartate (AST, SGOT)10 40 U/LAmmonia, blood40 70 g/dLAmylase, serum25 125 U/L (80 180 [Somogyi] units/dL)Amylase, urine1 17 U/hrAndrostenedione, serumFemale: 30 200 ng/dL; male: 40 150 ng/dLAngiotensin- converting enzyme, serum8 53 U/LAnion gap, serum7 13 mEq/LAntibodies to double-stranded DNA0 7 IU/mLABIM Laboratory Test Reference Ranges July 2021 Anticardiolipin antibodies IgG 20 GPL IgM 20 MPLAnti-cyclic citrullinated peptide, antibodies to 20 unitsAntideoxyribonuclease B 280 unitsAnti-F-actin antibodies, serum 1:80 Antihistone antibodies 1:16 Anti-liver-kidney microsomal antibodies (anti-LKM) 1:20 Antimitochondrial antibodies 1:5 Anti myelin associated glycoprotein antibody 1:1600 Antimyeloperoxidase antibodies UAntinuclear antibodies 1.

3 40 Anti smooth muscle antibodies 1:80 Antistreptolysin O titer 200 Todd unitsAntithrombin activity80% 120%Antithyroglobulin antibodies 20 U/mLAntithyroid peroxidase antibodies U/mLAnti-tissue transglutaminase antibodiesSee Tissue transglutaminase antibodyArterial blood gas studies (patient breathing room air): PaCO2 38 42 mm Hg PaO2 75 100 mm Hg Bicarbonate23 26 mEq/L Oxygen saturation 95% acid (vitamin C), mg/dLAscorbic acid, mg/dL of leukocytes(1,3)-Beta-D-glucan, serum 60 pg/mLBeta-human chorionic gonadotropin (beta-hCG), serumFemale, premenopausal nonpregnant: U/L ; female, postmenopausal: U/L.

4 Male: U/LBeta-human chorionic gonadotropin (beta-hCG), urine 2 mIU/24 hrBeta2-glycoprotein I antibodies: IgG 21 SGU IgM 21 SMUBeta-hydroxybutyrate, serum mmol/LBeta2-microglobulin, mg/LBicarbonate, serum23 28 mEq/LBilirubin, serum mg/dL mg/dL mg/dLBleeding time (template) 8 minutesBlood urea nitrogen (BUN), serum or plasma8 20 mg/dLB-type natriuretic peptide, plasma 100 pg/mLC peptide, ng/mLCalcitonin, serumFemale: 5 pg/mL; male: 10 pg/mLCalcium, ionized, mmol/LCalcium, mg/dL2 Calcium, urineFemale: 250 mg/24 hr; male: 300 mg/24 hrCarbohydrate antigens, serum CA 19-90 37 U/mL CA 27-29 U/mL CA 125 35 U/mLCarbon dioxide content, serum23 30 mEq/LCarboxyhemoglobin, blood 5%Carcinoembryonic antigen, plasma ng/mLCarotene, serum75 300 g/dLCatecholamines, plasma Dopamine 30 pg/mL Epinephrine Supine 50 pg/mL Standing 95 pg/mL Norepinephrine Supine112 658 pg/mL Standing217 1109 pg/mLCatecholamines.

5 Urine Dopamine65 400 g/24 hr Epinephrine2 24 g/24 hr Norepinephrine15 100 g/24 hr Total26 121 g/24 hrCD4 T-lymphocyte count530 1570/ LCell count, CSF: Leukocytes (WBCs)0 5 cells/ L Erythrocytes (RBCs)0/ LCeruloplasmin, serum (plasma)25 43 mg/dLChloride, CSF120 130 mEq/LChloride, serum98 106 mEq/L Chloride, urine Random ("spot")mEq/L; varies 24-hour measurementmEq/24 hr; varies with intakeCholesterol, serum Total Desirable 200 mg/dL Borderline-high200 239 mg/dL High>239 mg/dL High-density lipoprotein LowFemale: 50 mg/dL; male: 40 mg/dL Low-density lipoprotein Optimal 100 mg/dL Near-optimal100 129 mg/dL Borderline-high130 159 mg/dL High160 189 mg/dL Very high>189 mg/dLCholinesterase, serum (pseudocholinesterase) pH units/hr Packed cells pH units/hrChorionic gonadotropin, beta-human (beta-hCG), serumSee Beta-human chorionic gonadotropin (beta-hCG), serum3 Chorionic gonadotropin, beta-human (beta-hCG), urineSee Beta-human chorionic gonadotropin (beta-hCG), urineChromogranin A, serum 93 ng/mLCitrate, urine250 1000 mg/24 hrClotting time (Lee-White)

6 5 15 minutesCoagulation factors, plasma Factor I (fibrinogen)200 400 mg/dL Factor II (prothrombin)60% 130% Factor V (accelerator globulin)60% 130% Factor VII (proconvertin)60% 130% Factor VIII (antihemophilic globulin)50% 150% Factor IX (plasma thromboplastin component)60% 130% Factor X (Stuart factor)60% 130% Factor XI (plasma thromboplastin antecedent)60% 130% Factor XII (Hageman factor)60% 130% Factor XIII57% 192%Cold agglutinin titer>1:64 positiveComplement components, serum C3100 233 mg/dL C414 48 mg/dL CH50110 190 units/mLCopper, serum100 200 g/dLCopper, urine0 100 g/24 hrCoproporphyrin, urine50 250 g/24 hrCortisol, free, urine4 50 g/24 hrCortisol, plasma 8 AM5 25 g/dL 4 PM 10 g/dL 1 hour after cosyntropin 18 g/dL Overnight suppression test (1-mg) g/dL Overnight suppression test (8-mg)>50% reduction in cortisolCortisol, saliva, 11 PM midnight g/dLC-reactive protein, serum mg/dLC-reactive protein (high sensitivity), serumLow risk = mg/L; Average risk = mg/L.

7 High risk = > mg/LCreatine kinase, serum TotalFemale: 30 135 U/L; male: 55 170 U/L MB isoenzymes 5% of totalCreatine, urineFemale: 0 100 mg/24 hr; male: 0 40 mg/24 hrCreatinine clearance, urine90 140 mL/ m2 Creatinine, serumFemale: mg/dL; male: mg/dLCreatinine, urine Random ("spot")mg/dL; varies 24-hour measurement15 25 mg/kg body weight/24 hrCyclosporine, whole blood (trough) Therapeutic100 200 ng/mL 0 3 months post transplantation150 250 ng/mL More than 3 months post transplantation75 125 ng/mLD-dimer, plasma g/mLDehydroepiandrosterone sulfate (DHEA-S), serumFemale: 44 332 g/dL.

8 Male: 89 457 g/dL4 Delta-aminolevulinic acid, serum 20 g/dLDigoxin, serumTherapeutic: ng/mL ( ng/mL for patients with heart failure)Dihydrotestosterone, serumAdult male: 25 80 ng/dLDopamine, plasma 30 pg/mLDopamine, urine65 400 g/24 hrD-Xylose absorption (after ingestion of 25 g of D-xylose) Serum25 40 mg/dL Urinary g during a 5-hr periodElectrolytes, serum Sodium136 145 mEq/L mEq/L Chloride98 106 mEq/L Bicarbonate23 28 mEq/LEpinephrine, plasma Supine 110 pg/mL Standing 140 pg/mLEpinephrine, urine 20 g/24 hrErythrocyte million/ LErythrocyte sedimentation rate (Westergren)Female: 0 20 mm/hr.

9 Male: 0 15 mm/hrErythrocyte survival rate (51Cr)T = 28 daysErythropoietin, serum4 26 mU/mLEstradiol, serum Female, follicular10 180 pg/mL Mid-cycle peak100 300 pg/mL Luteal40 200 pg/mL Postmenopausal 10 pg/mL Male20 50 pg/mLEstriol, urine>12 mg/24 hrEstrogen receptor proteinNegative: 10 fmol/mg proteinEstrone, serum10 60 pg/mLEthanol, blood ( 5 mg/dL) Coma level> (>500 mg/dL) Intoxication ( 80 100 mg/dL)Euglobulin clot lysis time2 4 hours at CEverolimus, whole blood (trough)Therapeutic: ng/mLFactor XIII, B subunit, plasma60 130 U/dLFecal fat 7 g/24 hrFecal nitrogen 2 g/24 hrFecal potassium 10 mEq/LFecal sodium 10 mEq/LFecal urobilinogen40 280 mg/24 hrFecal weight 250 g/24 hrFerritin, serumFemale: 24 307 ng/mL.

10 Male: 24 336 ng/mLFibrin(ogen) degradation products 10 g/mLFibrinogen, plasma200 400 mg/dLFibroblast growth factor-23, serum30 80 RU/mLFlecainide, serumTherapeutic: g/mL5 Folate, red cell150 450 ng/mL of packed cells Folate, ng/mLFollicle-stimulating hormone, serum Female, follicular/luteal2 9 mIU/mL (2 9 U/L) Female, mid-cycle peak4 22 mIU/mL (4 22 U/L) Female, postmenopausal>30 mIU/mL (>30 U/L) Male (adult)1 7 mIU/mL (1 7 U/L) Children, Tanner stages 1, mIU/mL ( U/L) Children, Tanner stages 3, 4, 51 12 mIU/mL (1 12 U/L)Free kappa light chain, mg/LFree kappa-to-free lambda light chain ratio, lambda light chain, mg/LGamma globulin, mg/dLGamma-glutamyltransferase (gamma-glutamyl transpeptidase), serumFemale.