Transcription of Aminoglycosides Macrolides Glycyclines Tract Agents TMP …
1 OrganismKetolideGlycyclinesGram PositiveGentamicinTobramycinAmikacinNeti lmicinChloramphenicolClindamycinErythro/ DirithroAzithromycinClarithromycinTelith romycinDoxycyclineMinocyclineTigecycline VancomycinTeicoplaninDalbavancinFusidic AcidTrimethoprimTMP-SMXN itrofurantoinFosfomycinRifampinMetronida zoleQuinupristin-dalfopristinLinezolidDa ptomycinColistimethate(Colistin)Strep, Group A,B,C,G0000++++++ - +++++ - +1++0+++0 Step. Pneumoniae0000++++++++++++ - - +++0+++0E. faecalisSSSS- 0000 - 00++++++1++ - 00++0E. faeciumS000 - 0000000+ - - -00+ - 00+++0 Staph. Aureus (MSSA)++++ - + - +++ - ++++++ - +++0+++0 Staph. Aureus (MRSA)0000000000 - -+++++ - +0+0+++0 Staph. Epidermidis- - - - 00 - 00000++ - +++ -+0+++0C. jeikeium000000000000+++++000+0+++0L. monocytogenesSSSS++++++++++++++0+++0 Gram NegativeN.
2 Gonorrhoeae0000+0 - - -- - +000+0 - +++0+00N. meningitidis0000+0+++++000+ - ++00000M. catarrhalis+++++0+++++++++0+ - 0H. influenzae+++++0 - ++++++- -+0 - - 0 Aeromonas0++++0+000E. coli+++++00000++0000++++00000+Klebsiella sp.++++ - 00000 - - +0000++ - - 00000+Enterobacter sp.++++00000000+0000 -- - 00000+Salmonella sp.+00 - 00 - - +0000 - - +00000 Shigella sp.+++++00 - 00 - - +0000 - - +00000 Serratia marcescens++++00000000+00000 - 0 - 0000 Proteus vulgaris++++ - 0000000 - 0000000 - 00000 Acinetobacter +00000000+0000000000+Ps. Aeruginosa++++000000000000000000000+B. (Ps.) cepacia0000+000000 - - 0000++000000S. (X.) maltophilia0000+0000000+00000+0000Y. enterocolitica++++00000000+000F. tularensis+++++000 Brucella sp.++00000++000+++000 Legionella sp.++++++- ++00H. ducreyi++++0-00V. vulnificus---+++00 MISC.
3 :Chlamydophilia + - +++++++000+0++M. pneumoniae0000+0+++++++00+Rickettsia +-+++00000 Mycobacterium avium+++000000 ANAEROBES:Actinomyces0000++++++++++0 Bacteroides fragilis0000+ - 000- - +00+0+-P. melaninogenica0000+++++++00+++Clostridiu m difficile0000 -++++ - -Clostridium (NOT difficile)+- ++++++++++++Peptostreptococcus ++ - + - ++++++++++MiscellaneousUrineary Tract AgentsAminoglycosidesMacrolidesTetracycl inesGlycopeptides+ = effective or > 60% susceptibility, - = clinical trials lacking or 30-60% susceptible, 0 = not effective or < 30% susceptibility, S = synergistic effect with pencillins (ampicillin), blank = data in not available. Azithromycin has high tissue penetration, and clarithromycin is metabolized into more active compounds, hence, in vivo may be far more effective than in vitro.
