Transcription of AREDS2とその研究結果がルテインとゼアキサンチンにもたら …
1 AREDS S. , MD, PhD AMD AMD 50 1 AMD oxygenated carotenoid AMD 1 1. 2 Tagetes erecta Lycium barbarum 2.
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7 Koushan K, Rusovici R, Li W, Ferguson LR, Chalam KV. The role of lutein in eye-related disease. Nutrients. 2013 May 22;5(5):1823-39. 2. Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Miller DT, Yannuzzi LA, Willett W. Dietary carotenoids, vitamin A, C, and E, and advanced age-related macular degeneration. JAMA. 1994;272:1413-20. 3. Semba RD, Dagnelie G. Are lutein and zeaxanthin conditionally essential nutrients for eye health? Med Hypotheses. 2003 Oct;61(4):465-72. 4. Hung RJ, Zhang ZF, Rao JY, Pantuck A, Reuter VE, Heber D, Lu QY. Protective effects of plasma carotenoids on the risk of bladder cancer. J Urol. 2006 Sep;176(3):1192-7. 5.
8 Dwyer JH, Paul-Labrador MJ, Fan J, Shircore AM, Merz CN, Dwyer KM. Progression of carotid intima-media thickness and plasma antioxidants: the Los Angeles Atherosclerosis Study. Arterioscler Thromb Vasc Biol. 2004 Feb;24(2):313-9. 6. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001 Oct;119(10):1417-36. 7. Paul S. Bernstein (No date) Nutrition and Macular Degeneration [Online] University of Utah Health Care. Available: [accessed 12 March 2014] 8. The Age-Related Eye Disease Study 2 (AREDS2) Research Group.
9 Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration. The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial. JAMA. 2013 May 15;309(19):2005-15. 9. Nolan JM, Akkali MC, Loughman J, Howard AN, Beatty S. Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment. Exp Eye Res. 2012 Aug;101:9-15. 10. Bhosale P, Larson AJ, Frederick JM, Southwick K, Thulin CD, Bernstein PS. Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye. J Biol Chem. 2004 Nov 19;279(47):49447-54. 11. Li B, Vachali P, Frederick JM, Bernstein PS.
10 Identification of StARD3 as a lutein-binding protein in the macula of the primate retina. Biochemistry. 2011 Apr 5;50(13):2541-9. 12. Bone RA, Landrum JT, Fernandez L, Tarsis SL. Analysis of the macular pigment by HPLC: retinal distribution and age study. Invest Ophthalmol Vis Sci. 1988 Jun;29(6):843-9. 13. Landrum JT, Bone R, Neuringer M, Cao Y. Macular pigment: From discovery to function. In: Landrum JT and Nolan JM, eds. Carotenoids and Retinal Disease. CRC Press; 2013. 9-11. 2014 3 25 SupplySide West 2013 VendorBrief Presentations 2013 11 15 Moran Eye Center, University of Utah S Paul S. Bernstein, MD, PhD Katra Phytochem Pvt.
