Autism - dramyyasko.com

1 Autism : Pathways to RecoveryDr. Amy YaskoNR INeu rological Research InstituteAutism: Pathways to RecoveryDr. amy yasko , CTN, NHD, AMD, HHP, FAAIMC opyright 2004, 2007, 2009 Neurological Research Institute, LLCW ithout limiting the rights under copyright reserved above, no part of this pub-lication may be reproduced, stored in or introduced into a retrieval system, or transmitted, in any form or by any means (electronic, mechanical, photocopying, recording or otherwise), without the prior written permission of both the copy-right owner and the above publisher of this book. The scanning, uploading, and distribution of this book via the Internet or via any other means without the permission of the publisher is illegal and punishable by law. Please purchase only authorized electronic editions and do not participate in or encourage electronic piracy of copyrightable materials.

2 Your support of the author s rights is EditionISBN: 978-1-4243-4320-1 Neurological Research InstituteBethel, Maine It is important for me to thank and appreciate those who make a positive difference in my life. To me, this is part of paying it forward, and in that light I would like to thank those whose love, help and support have given me the strength to put together a program to help all of Missie, Jessie, and Cassie. The joy, love and support I receive from my ownchildren inspires me and gives me the strength to help special word of thanks is owed to Edward yasko . He is my partner in life inevery sense of the word, and my work in this field would not be possible without his love and you to all the parents who share their stories of progress, hope, and yes,setbacks with the online discussion group.

3 The concept of paying it forward hashelped to make the group a haven for knowledge, support and you to all of our cyber moms, especially Erin for helping to make the discussion group a resource for emotional support and you to Cindy, Erin, Melissa, Marcy, LJ, and Peg for compiling the workbook to compliment this text; your contributions have helped to make this program easier to you to the entire office staff, Christine, Danielle, Kelly, Peter, Scott, Frances, JJ, Debbie, Mark and Nancy for showing compassion and caring beyond the call of you to Missie and Sergio for amazing graphics to help make this book easier to you to Alison Rose Levy for her professional expertise in helping to write this book so that it can reach a larger loving memory of my OF CONTENTSI. Foundations of a New ApproachChapter 1.

4 Discovering the Pathways .. 1 THE Autism EPIDEMIC .. 1A Paradigm Shift .. 2 Living with Autism .. 2 Recovery Is Possible .. 2 How I Evolved My Approach .. 4 Working With a Practitioner .. 6 Using This Book as a Guide .. 6 The Core Science .. 7 Following the Program .. 8 The Complexity of Modern Life .. 8 The Complexity of Modern Ailments .. 9 The Myth of the Magic Bullet .. 10 Beyond the Single Cause and Cure .. 11 Where to Begin? .. 12 THE PUZZLE OF Autism .. 12 Multifactorial Effects .. 13 Individualized Treatment .. 14 Understanding the Pieces of the Puzzle .. 14A BRIEF REVIEW .. 16 BOOK OVERVIEW .. 17MY PROMISE TO YOU .. 18 Autism : Pathways to RecoveryIIChapter 2. Nutrigenomics and the Methylation DAWNING OF THE AGE OF PERSONALIZED MEDICINE.

5 19 NEUROLOGICAL INFLAMMATION .. 21 THE NEW SCIENCE OF NUTRIGENOMICS .. 23 Genetic Testing .. 24 Why Do We Need Methylation? .. 25 Which Genes Should We Test? .. 26 Autism : A MULTIFACTORIAL CONDITION .. 26 METHYLATION IS THE MESSAGE .. 28 Repairing and Building DNA .. 29 Immune Function .. 30 Digestive Issues .. 31 DNA Silencing .. 32 Neurotransmitter Balance .. 32 Metal Detoxification .. 34 Inflammation .. 38 Membrane Fluidity .. 41 Energy Production .. 41 Protein Activity .. 42 Myelination .. 42 THE ROLE OF METHYLATION IN HEALTH CONDITIONS 43 Cancer .. 43 Pregnancy Risks .. 43 AGING .. 44 Infections, Bacteria, and Viruses .. 44 METHYLATION: NATURE VS. NURTURE .. 44 MEET THE SNPS .. 46 Why Gene Testing? .. 47 The Alphabet of Genes .. 48 SNPs and the Methylation Pathway.

6 49 Basic SNPs .. 50 Chapter 3. Promoting Detoxification Safely .. 55 GENETIC FACTORS .. 55 ENVIRONMENTAL FACTORS .. 56 The Invisible Burden .. 56 Key Environmental Toxins .. 57 Toxic Metals and Neurological Inflammation .. 59 INFECTIOUS AGENTS .. 60 Strep and Gut Bacteria .. 62 Vaccination-Induced Viral Load .. 62 Herpes Viruses .. 63 Other Chronic Viral Infections .. 63 Microbes and Metals .. 64 TRACKING DETOXIFICATION .. 69 Patterns of Metal Elimination .. 70 Using Creatinine to Monitor Progress .. 71 Autism : Pathways to RecoveryIVCONCLUSION .. 71II. Implementing the New Approach .. 73 Chapter 4. Step One, Part One Building a Foundation for Health Balance .. 75 BASELINE TESTS .. 76A THREE-STEP PROGRAM .. 76 Step One Overview .. 76 Step Two Overview .. 77 Step Three Overview.

7 78 STEP ONE: PREPARING FOR THE PROGRAM .. 78 Basic Supplement Support .. 79 Why We Use So Many Supplements .. 81 Diet and Food Reactions .. 82 CONTROLLING EXCITOTOXINS .. 85 Neurotransmitters: Balancing GABA & Glutamate .. 85 How Glutamate Harms Nerve Cells .. 88 TOXIC FOOD INGREDIENTS .. 97 Foods to Avoid .. 99 CONCLUSION .. 102 Chapter 5. Promoting Healthy Digestion .. 103 THE LIVER .. 104 THE KIDNEYS .. 105 THE PANCREAS .. 106 THE DIGESTIVE TRACT .. 107 What s Going on Inside Leaky Gut? .. 107 Addressing Gut Imbalancess .. 109 Excess Acid .. 109 Key Factors for Gut Health .. 111 Summary of Gut Program .. 116 Chapter 6. Step Two, Part One Optimizing the Methylation Cycle .. 117 UNDERSTANDING DETOXIFICATION .. 117 MONITORING YOUR MINERALS .. 118 ARE YOU READY TO BEGIN STEP TWO?

8 121 Adding Supplements .. 121 Bypassing Mutations .. 121 UNDERSTANDING YOUR TEST RESULTS .. 123 How to Read the Nutrigenomic Test .. 124 STEP TWO: WHERE TO BEGIN .. 125 Overview of the Mutations .. 127 FIRST PRIORITY MUTATIONS .. 127 Addressing SHMT and ACAT Mutations .. 127 Addressing CBS Mutations .. 129 The BH4 Three-Legged Stool .. 135 SECOND PRIORITY MUTATIONS .. 139 Autism : Pathways to RecoveryVIMethylation Cycle Overview .. 139 COMT Status .. 142 MTR/MTRR Status .. 144 MTHFR Status .. 148 TRACKING METHYLATION STATUS WITH TESTS .. 151 SUPPORTING THE SHORTCUT .. 152 BHMT Status .. 153 OTHER IMPORTANT GENES .. 153 MaoA .. 153 SUOX .. 154 NOS .. 157 The ACE Deletion .. 157 PEMT .. 159 STRENGTHENING ALL PARTS OF THE CYCLE .. 160 Revisiting Gut Support.

9 160 Mitochondrial Support .. 160 Decreased G6 PDH Activity .. 162 Glutathione Support .. 163 Urea Cycle Support .. 164 General Amino Acid Support .. 166 Chapter 7. Step Two, Part Two Increasing Detoxification .. 169 WHEN TO UNDERTAKE THE METALS PROGRAM .. 169 Metals and Microbes .. 170 PREPARING FOR THE METALS PROGRAM .. 171 Supplements to Promote Detoxification .. 172 RNA Formulas .. 173 Immune Factors .. 174 STARTING THE METALS I PROGRAM .. 174 Tracking Detox .. 175 Interim Between Metals I and Metals II Programs .. 176 THE METALS II RNA PROGRAM .. 177 THE METALS III RNA PROGRAM .. 178 THE METALS IV RNA PROGRAM .. 178 IMMUNE FACTORS .. 180 MANAGING DETOX .. 181 Supports for Symptoms .. 182 The Clean Up .. 184 ADDITIONAL FACTORS .. 187 Addressing Strep.

10 187 Infections and the Thyroid .. 188A Few Pointers About Aluminum .. 189A WORD ON DETOX .. 190 Chapter 8. Step Three Remyelinating the Nerves .. 191 BEGINNING THIS STEP .. 191 Autism : Pathways to RecoveryVIIIS uggested Protocol to Support Nerve Growth and Myelination 192 Changes in Mood and Behavior .. 196 ADDITIONAL THERAPIES .. 198IN CONCLUSION .. 199 III. Walking the Pathways to Recovery .. 201 Chapter 9. Stories of Hope Rewarded .. 203 Jonathan s Story .. 203 Luke s Story .. 205 Lake's story .. 207 Heathar-Ashley s Story .. 207 Aliva's Story .. 208 Anne s Story .. 210 Drake and Blaise s Story .. 210 Mit s Story .. 212 Cameron s Story .. 213 Joey s Story .. 216 Chris s Story .. 219 Brendan and Kyle s Story .. 220 APPENDIX: FLOW CHART FOR MICROBES .. 222In most cases the forward of a book is not written by its author.