新血管指標AVI APIのご紹介

1 AVI API 2021/7/8 WHO/ISH / (1999) Stiffness) baPWV 2 API,AVI 2011 PMDA PASESA PASESA PWV/ABI API,AVI PWV/CAVI FMD RH-PAT IMT AI/ AI/ baPWV CAVI Stiffness PWV= (L) t baPWV( cfPWV( ESH2007 cfPWV ( sec mm ( mm/sec)))

2 Aba, b PWV PWV pulse Wave velocity ( ) baPWVbaPWV Vf Vr (Vr/Vf) AVI 20 (Vr/Vf) ( ( (P2) (P1) Vr/Vf P1P2 P2 AVI Arterial velocity pulse Index) A*arctan(B*X+C)+D API 1/B API Arterial Pressure volume Index)

3 (B 29 25 4 2021/6/25 Successful prediction of clinical outcomes usingarterial velocity pulse index, a new non-invasivevascular index, in Japan AVI 2019 AVI CV ( Association between novel arterial stiffness indicesand risk factors of cardiovascular disease 2016 SD = 4083 3165 CVD( Screening Validity of Arterial Pressure-Volume Indexand Arterial velocity - pulse Index for PreclinicalAtherosclerosis in Japanese Community-DwellingAdults.)))

4 The Nagasaki Islands Study 2018 2,809 68 API AVI CIMT( B = P = B = P = API AVI 31[ AUC ] 29 AUC Increased arterial velocity pulse index is anindependent factor related to skeletal muscle massreduction and tissue damage in patients withcardiovascular disease AVI 2020 CVD( AVI 2021 mg AVI 23 2018 API,AVI))

5 New indices of arterial stiffness measured with anupper-arm oscillometric device in active versusinactive women 2018 AVI API AVI API PASESA AV I API 2 S G LT 2 AVI,API API PWV AV I 1 AV I API,AVI AV I Successful Prediction of Clinical Outcome by New Non-Invasive Vascular IndexesRieNakashima 1 TomoakiIshigami1 TabitoKino 1 Lin Chen 1 Hiroshi Doi 1 ShintaroMinegishi 1 TeruyasuSugano 1 Koichi Tamura 11.

6 Department of Medical Science and Cardiorenal Medicine,YokohamaCity University Graduate School of Medicine, Yoko-hamaJCS2017 AV I API AV I BNP API FCVRS Nakashima Journal of Cardiology 2016 AV I API 180 66 13 MACE 769 MACE 13 MACE AV I MACE p = AV I MACE p = HF p = MACE AVI 27 AVI 27 Association between novel arterial stiffness indices and risk factors of cardiovascular disease.

7 BMC Cardiovascular Disorders (2016) 16:211 Masaki Okamoto , Fumiaki Nakamura, TerunagaMushaand YasukiKobayashi 1 7248 4083 3165 API AV I t ICC API ICC AV I ICC AVI,API CVD Screening Validity of Arterial Pressure-Volume Index and Arterial velocity - pulse Index for Preclinical Atherosclerosis in Japanese Community-Dwelling Adults.

8 The Nagasaki Islands StudyJ AtherosclerThromb. 2018 Feb 3. doi: 2014 2016 40 2,809 1076 1733 CIMT mm CIMT API AV I CIMT API AV I (CAVI) API AV I surrogate end point Arterial Stiffness Measured with the Cuff Oscillometric Method Is Predictive of Exercise Capacity in Patients with Cardiac DiseasesYasushi Tazawa, Nobuyoshi Mori, Yoshiko Ogawa, Osamu Ito and Masahiro KohzukiTohoku J.

9 Exp. Med., 2016, 239,O 1s2c7il-lo1m34etrically 116 CAD 34 CAD 82 CAD CAD AV I CAD CAD P < AV I VO2 r = P < VO2 = t = P < AV I CAD CAD CAD AVI,API 4054884,4144807,4253683,4646195 ,4747312, 5144725,4854014,6218267 US8251910B2, US8652055B2, US9730594B2,10506932B2 (USA)2676514(RUSSIA),ZL2007 8 , ZL2008 8 ,ZL2014 8 (CHINA) , EP2345365(EU)

10 29 25, 4 1988 1995 Cardiovision2004 2 API AVI 2008 AVI 2012 2014 DVT 2016 PASESA 2017 CYBERDYNE 2021 PASESA PASESA PASESA 1988 1 2-2-5 OEM