Transcription of Azithromycin
1 2018 3 7 . 2017 8 .. 876149. 250mg 500mg 22500 AMX01716000 22500 AMX01717000. 2013 12 2013 12 . 2013 12 2013 12 . 2016 10 . 15 . 250mg . 500mg . Azithromycin .. 250mg 500mg .. 1 1.. 250mg 500mg . 1 .. 2. 250mg .. 298mg 592mg . 250mg 500mg .. 500mg 1 1 . 3 .. 789 790 .. 250 500 1000mg 1 .. 789 790. 500mg 1 1 . 3 .. 250mg 500mg . 1000mg 1 .. 250mg . 1 1 .. 1.. 2. 4 .. 2 4 .. 1 . 3. 500mg 3.. 1 1 3 1 . 7 .. 3 . 1000mg 1 . 2 .. 10 . 1 . 4.. 3 4 .. P450 .. 5.. 10 .. 2 5 . P450 . 7 10 10 .. 250mg .. 1 1200mg . 2 7 . 7 . 6. AUC .. 5 . 7. 250mg P- .. 6 .. 1.. 1 . 2 . 2 . P450 . 1 . 3 QT Torsades de . pointes . 2. 2 . 1 3 .. 2 Toxic . Epidermal Necrolysis TEN . Stevens- . Johnson .. 3 . 4.. 1 . 1 .. 4 . 2 Toxic Epidermal Necrolysis TEN .. Stevens-Johnson . 5 .. 1 .. 2 . 3 7 .. 6 HHV 6 .. 4 .. 5 .. 1 . 6 2 . 5.. 7 . X .. 8 QT Torsades de pointes . QT Torsades de pointes .. QT 6.. 9 1 .. 10 2 . 8.
2 CK CPK .. 7.. 1 . 2 . 2 . 442 33 9 . 1000/mm3 . 7 8 . 1 .. 2 . 2 3 . 2 124 8 2 602 6 .. 4 . ALT GPT AST GOT Al-P . -GTP LDH . 8.. BUN 1 .. 2 .. 2 .. 2 .. 3 . 9.. 2R,3S,4S,5R,6R,8R,11R,12R,13S,14R . -5- 3,4,6-Trideoxy-3- dimethylamino- -D-xylo-hexopyranosyloxy -3- PTP PTP 2,6-dideoxy-3-C-methyl-3-O-methyl- -L-ribo- PTP hexopyranosyloxy -10-aza-6,12,13-trihydroxy- 2,4,6,8,10,11,13-heptamethylhexadecan-14 -olide dihydrate . 10.. 1 2 2 . 20mg/kg .. 2 20 100mg/kg 1 6 .. 3 .. C38H72N2O12 2H2O. 1.. 500mg 1 2 . 500mg .. AUC Cmax . 90 log . log 9 40 75 6 . 250mg 250mg . 18 11 500mg 3 . 24 1124004 12 . 500mg . 9 .. 250mg . 500mg . 60 6 10 PTP . 60 6 10 PTP . AUC0 72 Cmax Tmax t1/2 500mg . ng hr/mL ng/mL hr hr 30 3 10 PTP . 30 3 10 PTP . 3606 983 500mg .. 3805 910 250mg 2 1 . 500mg Mean , n 39 . 2 Foulds, G. et al. J Clin Pharmacol, 31 2 , 164, 1991. 3 Woldtvedt, et al. Ann Pharmacother, 32 2 , 269, 1998.
3 4 Lane, G. Ann Pharmacother, 30 7/8 , 884, 1996. 5 Amsden, et al. J Clin Pharmacol, 40 12- 2 , 1522, 2000. 6 Gomes, T. et al. Clin Pharmacol Ther, 86 4 , 383, 2009. 7 .. 8 Kelsey, J. et al. Am J Obstet Gynecol, 170 5 - 1 , 1375, 1994. 9 . 10 . 11 C-55 2016 . 12 .. AUC Cmax . 930-8583 1 6 21. 2. 0120 517-215. 250mg Fax 076 442-8948. 4 . 10 .. 70S 50S .. 11 .. Azithromycin Hydrate . AZM. 4 0321165-8.
