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Biotransformation: Phase I and Phase II Metabolism
an antidepressant that is converted to desimipramine through oxidative N-dealkylation. o ... are carried out by a family of enzymes known as Cytochrome P450 enzymes. These are often referred to as simply P450 enzymes or CYP. The remaining 5% of the ... gives rise to significant drug-drug interactions. o o CYP3A4: ...
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