Blood Management System - JMS North America

1 Blood ManagementSystemJMS designs up-to-dateblood Management productswith our patients and donors in for your healthJMS started manufacturing Blood bags in 1969 and have now over four decadesof extensive and relevant expertise to meet the challenges presented in research,development and production of medical devices for Blood transfusion bags manufactured by JMS have a long and laudable reputation for reliability,superior product quality and assurance. Certi ed under EN ISO13485 Quality System ,our fastidious production practices and high standards of quality control andmeasures in place are driven to ensure that our products meet the stringentrequirements of Blood banks and transfusion services which provide lifelinesservices to hospitals.

2 Patients and JMS we believe in This is our responsible Management of whole Blood and its components to ensuremore e ective use of precious Blood resources for better health care in today stransfusion usPg 2 JMS Complete Range ofBlood Management Systempage page 2463578101112152316149 About JMSS afety FeaturesEnhanced FeaturesBlood Banking AccessoriesProduct Conf igurationsCPD-SAGM SystemT-BEXS (CPD-SAGM)Whole Blood In-line FilterCord Blood Bag Collection SetAutologous BagCellaid Serum Collection BagPlatelet Storage BagDockable Red Cell Leuko-Filtration SystemWhole Blood In-line Leuko-Filtration SystemContentPg 3 ConvenienceJMS Integrated Blood Sampling Port Closed System & reusable Blood sampling with vacuum tube Option to have lidReliabilityJMS Blood Sampling Bag Storage container for convenient and contamination free sampling Volume of diverted Blood could be used for laboratory testingSafetyJMS Needle Protector Anti-stick

3 Device to provide healthcare workers and end -users maximum protection from needle stick injurySafe and e ective Blood transfusionSafety First. Our concern is not only to guarantee high quality of the bloodcomponents but also to provide maximum safety during Blood donationand sample 4 Superior red Blood cellviability for 42 daysstorageIncreased plasmayieldRed Blood cell owproperty comparableto whole bloodPlatelet storage for upto 5 daysThe System consists of a primary bag containing anticoagulant CPD solution and one satellite bag containingSAGM (saline-adenine-glucose-mannitol) red cell preservation solution.

4 This additive solution maintains redblood cell (RBC) viability and lowers the hematocrit of the RBC unit. Consequently JMS CPD-SAGM systemcan store RBCs for 42 days while maintaining 80% of post transfusion RBC survival additive-solution System also allows larger volume of plasma to be collected. The removal of bu y coatand preparation of platelet concentrates from the bu y coat are easily achieved using this System . JMS CPD-SAGM System includes a bag with high gas permeability which enables it to store viable platelets for up to5 SYSTEMPg 5 Compatible with mostcommercial automaticextractorsPre-attached bloodsampling port for exibilityNeedle protector forenhanced user safetyJMS T-BEX (Top and Bottom Extraction) System provides greater e cacy in the separation of Blood componentsafter centrifugation process.

5 It is common for Blood banks to use automatic processing machines to standardizeand save manual labour in the extraction of quality Red Blood Cell, Plasma and Platelets from collected System focuses on the use of the primary bag with Top and Bottom outlet ports which are mounted onthe extractor unit after centrifuge. Using a single press operation, the Platelet-Poor-Plasma is transferred to theupper transfer bag and the Red Cell Concentrate is pressed concurrently into the lower bag that containsSAGM solution for the preservation of red cells. The bu y coat is retained in the primary bag for subsequentpreparation of Platelets and (CPD-SAGM)

6 Pg 6 Ease of applicationStart and forget,hands freeSafe and ease handlingof System with in-line ltersAuto-venting loopsystemEnhanced uidrecoveryThe world-wide demand for leuko-reduced whole Blood has encouraged JMS to develop Blood bag systemsthat meet the regulatory guidelines and strict requirements of Blood banks especially in Europe and the of leukocyte contamination in Blood components is important to minimize various side e ectssuch as non-hemolytic febrile transfusion reactions, transmission of leukocyte-borne virus and preventionof HLA alloimmunization and platelet line with our commitment to continuous improvement and safe patient care.

7 We have designed a completeblood bag System for whole Blood ltration that facilitates the handling in whole Blood ltration to meet theEU Standards and AABB requirements regarding safe and e cient Blood IN-LINE LEUKO-FILTRATIONSYSTEMPg 7high yield of plasma- factor VIIIHigh ef f iciency ofleukocyte removalexcellent viability ofred cells for 42 daysstorageRigorous and advanced tests in our JMS research and development institutes as well as in practical use ofblood banks have shown that the LEUKOSEP In-line Filter for whole Blood combined with our well-establishedblood bag systems provide a high yield of plasma.

8 This includes a yield of Factor VIII, excellent viability of redcells and removal e ciency of certi ed production System includes strict quality assurance, guaranteed with a continuous high andconsistent quality level. The steam sterilization of the complete System and e cient coiling of the bag, lterand tubes assure high integrity of the lter, which provides ease in handling for the donation Blood IN-LINE FILTERF ilter Performance< hemolysisminimum haemoglobin contentof 40 g per unit> 85% red cell recoveryResidual hold upvolume < 45ml< 30 min ltration time< 1 x 106 leukocytes per unitThe multi layered ceramic based micrco- bres have proven in tests as well as in practise excellentperformance in ltration of whole Blood .

9 * Meeting the guidelines in the Council of EuropePg 8 Application Red Cell ConcentrateVolume Derived from 1 unit of 450 - 500ml +/- 10% Whole BloodFilter Performance Residual Hold UpVolume < 45mlLeukocyte Removal Rate < 1 x 106/unitRed Cell Recovery > 85%Post Filtration Hemolysis < Time < 30 mins (if processed at room temp) < 1 hr (if processed in 2-6 deg C)Post Donation Storage Duration =/< 5 days.

10 Maximum 8 hrs hold at temp prior to whole Blood centrifugationPost Donation Storage TemperaturePerformance Parameters 2 - 6 deg CState-of-the-artcollection, ltration andstorageUser-friendly,safe and fasthandling ofsystemsSuperb airventing systemTubing compatiblewith sterile deviceconnectionJMS Leukoreduction and Storage Set for Red Cells is a sterile disposable device intended for reducingleukocytes from a unit of red Blood cell. This design provides a safe, e ective and convenient collection ofred cells coupled with high e ciency leukocyte ltration RED CELL LEUKO-FILTRATIONSYSTEMPg 9 Tubing compatible withsterile device connectionSpecially tailored volumeof anticoagulantSafe Blood collectionusing attached needleprotectorDirect sampling withsyringe.