ChemDraw User’s Manual

1 ChemDrawChemical Structure Drawing Standard ChemDrawChemical Structure Drawing Standard CS ChemDraw Windows and MacintoshChemDrawis a standalone application within ChemOffice,an integrated suite including Chem3 Dfor molecular modeling and analysis, BioAssay for biological data retrieval and visualization,Inventory for managing and searching reagents,E-Notebookfor electronic journal and information,ChemFinderfor searching and information integration, andChemInfofor chemical and reference s Guide License InformationChemOffice, ChemDraw , Chem3D, ChemFinder, and ChemInfo programs, all resources in the ChemOffice, ChemDraw , Chem3D, ChemFinder, and ChemInfo application files, and this Manual are Copyright 1986-2004by CambridgeSoft Corporation (CS) with all rights reserved worldwide. MOPAC 2000 and MOPAC 2002 areCopyright 1993-2004 by Fujitsu Limited with all rights reserved.

2 Information in this document is subject tochange without notice and does not represent a commitment on the part of CS. Both these materials and the rightto use them are owned exclusively by CS. Use of these materials is licensed by CS under the terms of a software licenseagreement; they may be used only as provided for in said , ChemDraw , Chem3D, CS MOPAC, ChemFinder, Inventory, E-Notebook, BioAssay, and ChemInfoare not supplied with copy protection. Do not duplicate any of the copyrighted materials except for your personalbackups without written permission from CS. To do so would be in violation of federal and international law, andmay result in criminal as well as civil penalties. You may use ChemOffice, ChemDraw , Chem3D, CS MOPAC,ChemFinder, Inventory, E-Notebook, BioAssay, and ChemInfo on any computer owned by you; however, extracopies may not be made for that purpose.

3 Consult the CS License Agreement for Software and Database Productsfor further , ChemDraw , Chem3D, ChemFinder, ChemInfo and ChemACX are registered trademarks ofCambridgeSoft Corporation (Cambridge Scientific Computing, Inc.).The Merck Index is a registered trademark of Merck & Co., Inc. 2001 All rights 2000 and MOPAC 2002 are trademarks of Fujitsu Windows, Windows NT, Windows 95, and Microsoft Word are registered trademarks of Microsoft Corp. Apple Events, Macintosh, Laserwriter, Imagewriter, QuickDraw and AppleScript are registered trademarks of AppleComputer, Inc. Geneva, Monaco, and TrueType are trademarks of Apple Computer, ChemSelect Reaction Database is copyrighted by InfoChem GmbH is copyrighted by 1986-2004 CambridgeSoft Corporation (Cambridge Scientific Computing, Inc.) All Rights in the United States of other trademarks are the property of their respective End- user License Agreement for Software ProductsImportant:This CambridgeSoft Software License Agreement ( Agreement ) is a legal agreement between you, theend user (either an individual or an entity), and CambridgeSoft Corporation ( CS ) regarding the use of CS SoftwareProducts, which may include computer software, the associated media, any printed materials, and any online orelectronic documentation.

4 By installing, copying, or otherwise using any CS Software Product, you signify that youhave read the CS End user License Agreement and agree to be bound by its terms. If you do not agree to theAgreement s terms, promptly return the package and all its contents to the place of purchase for a full Software License 1. Grant of (CS) Software Products are licensed, not sold. CS grants and you hereby accepta nonexclusive license to use one copy of the enclosed Software Product ( Software ) in accordance with the termsof this Agreement. This licensed copy of the Software may only be used on a single computer, except as providedbelow. You may physically transfer the Software from one computer to another for your own use, provided theSoftware is in use (or installed) on only one computer at a time.

5 If the Software is permanently installed on your com-puter (other than a network server), you may also use the Software on a portable or home computer, provided thatyou use the software on only one computer at a time. You may not (a) electronically transfer the Software from onecomputer to another, (b) distribute copies of the Software to others, or (c) modify or translate the Software withoutthe prior written consent of CS, (d) place the software on a server so that it is accessible via a public network such asthe Internet, (e) sublicense, rent, lease or lend any portion of the Software or Documentation, (f ) modify or adaptthe Software or merge it into another program, (g) modify or circumvent the software activation, or (h) reverse engi-neer the software activation so as to circumvent it. The Software may be placed on a file or disk server connected toa network, provided that a license has been purchased for every computer with access to that server.

6 You may makeonly those copies of the Software which are necessary to install and use it as permitted by this agreement, or are forpurposes of backup and archival records; all copies shall bear CS s copyright and proprietary notices. You may notmake copies of any accompanying written materials. With a fixed license, the software cannot be installed on more than the number of computers equivalent to the num-ber of fixed licenses purchased. For example, a 10- user fixed license means the software can be installed on no morethan 10 different computers. A fixed license cannot be installed on a server. With a concurrent license, the softwarecan be installed on any number of computers at the organization, but the number of computers using the softwareat any one time cannot exceed the number of concurrent licenses purchased. For example, a 10- user concurrentlicense can be installed on 20 computers, but no more than 10 users can be using it at any one time.

7 If the numberof users of the software could potentially exceed the number of licensed copies, then Licensee must have a reasonablemechanism or process in place to assure that the number of persons using the software does not exceed the numberof copies. CambridgeSoft reserves the right to conduct periodic audits no more than once per year to review theimplementation of this agreement at the Licensee s site. At CambridgeSoft s request, Licensee will provide a knowl-edgeable employee to assist in said audit2. Software is and at all times shall remain the sole property of CS. This ownership is protected bythe copyright laws of the United States and by international treaty provisions. Upon expiration or termination of thisagreement, you shall promptly return all copies of the Software and accompanying written materials to CS. You maynot modify, decompile, reverse engineer, or disassemble the Assignment may not rent, lease, or otherwise sublet the Software or any part thereof.

8 You maytransfer on a permanent basis the rights granted under this license provided you transfer this Agreement and all copiesof the Software, including prior versions, and all accompanying materials. The recipient must agree to the terms ofthis Agreement in full and register this transfer in writing with Use of Included Data. All title and copyrights in and to the Software product, including but not limited to anyimages, photographs, animations, video, audio, music, text, applets, Java applets, and data files and databases (the Included Data ), are owned by CS or its suppliers. You may not copy, distribute or otherwise make the Included Data publicly available. Licensed users of ChemOffice Enterprise and Workgroup and the accompanying Plugin software products mayaccess, search, and view the Included Data and may transmit the results of any search of the Included Data to otherusers of the licensed ChemOffice Enterprise and Workgroup software products within your organization only, providedthat such transmission is via an internal corporate (or university) network and is not accessible by the public.

9 You may not install the Included Data on non-licensed computers nor distribute or otherwise make the IncludedData publicly available. You may use the Software to organize personal data, and you may transmit such personal data over the Internet pro-vided that the transmission does not contain any Included Data. All rights not specifically granted under this Agreement are reserved by Separation of Software is licensed as a single product. Its component parts may not be sepa-rated for use on more than one computer, except in the case of ChemOffice Enterprise. ChemOffice Enterpriseincludes licenses for ChemDraw ActiveX and licenses for Chem3D ActiveX. The ActiveX software products may beinstalled on computers other than that one on which ChemOffice Enterprise is installed. However, each copy of theActiveX is individually subject to the provisions of Paragraphs 1 through 4 of this Educational Use Only of Student you are a student enrolled at an educational institution, the CSLicense Agreement grants to you personally a license to use one copy of the enclosed Software in accordance with theterms of this Agreement.

10 In this case the CS License Agreement does not permit commercial use of the Software nordoes it permit you to allow any other person to use the Software. 7. may terminate the license at any time by destroying all copies of the Software and documenta-tion in your possession. Without prejudice to any other rights, CS may terminate this Agreement if you fail to com-ply with its terms and conditions. In such event, you must destroy all copies of the Software Product and all of itscomponent Confidentiality. The Software contains trade secrets and proprietary know-how that belong to CS and arebeing made available to you in strict USE OR DISCLOSURE OF THE SOFTWARE, OR USE OF ITSALGORITHMS, PROTOCOLS OR INTERFACES, OTHER THAN IN STRICT ACCORDANCE WITH THIS LICENSEAGREEMENT, MAY BE ACTIONABLE AS A VIOLATION OF OUR TRADE SECRET Limited WarrantyLimited s sole warranty with respect to the Software is that it shall be free of errors in program logicor documentation, attributable to CS, which prevent the performance of the principal computing functions of theSoftware.