Transcription of CLINICAL GUIDELINES
1 CLINICAL GUIDELINES . Oncology Imaging GUIDELINES Version Effective January 1, 2022. eviCore healthcare CLINICAL Decision Support Tool Diagnostic Strategies: This tool addresses common symptoms and symptom complexes. Imaging requests for individuals with atypical symptoms or CLINICAL presentations that are not specifically addressed will require physician review. Consultation with the referring physician, specialist and/. or individual's Primary Care Physician (PCP) may provide additional insight. eviCore's CLINICAL Review Criteria ( CRC ) and related content is made available for the limited uses of: reference; and individual use, only limited to facilitating the determination of medically necessary and appropriate CLINICAL treatment by clinicians for specific delegated patients under their care.
2 The CRC and related content is proprietary information of eviCore, and copyrighted to the full extent of the law. Except as expressly permitted, you may not modify, copy, reproduce, republish, upload, post, transmit, hyperlink to or from, or distribute in any way the CRC, nor may you sell, transfer, distribute, assign, lease, reproduce, or otherwise use the CRC in commerce, in a manner that competes with us or infringes upon our rights, or for any public or commercial endeavor without our prior and express written consent. CPT (Current Procedural Terminology) is a registered trademark of the American Medical Association (AMA). CPT five digit codes, nomenclature and other data are copyright 2021 American Medical Association.
3 All Rights Reserved. No fee schedules, basic units, relative values or related listings are included in the CPT book. AMA does not directly or indirectly practice medicine or dispense medical services. AMA assumes no liability for the data contained herein or not contained herein. 2021 eviCore healthcare. All rights reserved. Oncology Imaging GUIDELINES Oncology Imaging GUIDELINES Abbreviations for Oncology GUIDELINES ONC-1: General GUIDELINES ONC-2: Primary Central Nervous System Tumors ONC-3: Squamous Cell Carcinomas of the Head and Neck ONC-4: Salivary Gland Cancers ONC-5: Melanomas and Other Skin Cancers ONC-6: Thyroid Cancer ONC-7: Small Cell Lung Cancer ONC-8: Non-Small Cell Lung Cancer ONC-9: Esophageal and GE Junction Cancer ONC-10: Other Thoracic Tumors ONC-11: Breast Cancer ONC-12: Sarcomas Bone, Soft Tissue and GIST.
4 ONC-13: Pancreatic Cancer ONC-14: Upper GI Cancers ONC-15: Neuroendocrine Cancers and Adrenal Tumors ONC-16: Colorectal and Small Bowel Cancer ONC-17: Renal Cell Cancer (RCC). ONC-18: Transitional Cell Cancer ONC-19: Prostate Cancer ONC-20: Testicular, Ovarian and Extragonadal Germ Cell Tumors ONC-21: Ovarian Cancer ONC-22: Uterine Cancer ONC-23: Cervical Cancer ONC-24: Anal Cancer & Cancers of the External Genitalia ONC-25: Multiple Myeloma and Plasmacytomas ONC-26: Leukemias, Myelodysplasia and Myeloproliferative Neoplasms ONC-27: Non-Hodgkin Lymphomas ONC-28: Hodgkin Lymphoma ONC-29: Hematopoietic Stem Cell Transplantation ONC-30: Medical Conditions with Cancer in the Differential Diagnosis ONC-31: Metastatic Cancer, Carcinoma of Unknown Primary Site, and Other Types of Cancer ONC-32: Medicare Coverage Policies for PET.
5 _____. 2021 eviCore healthcare. All Rights Reserved. Page 2 of 309. 400 Buckwalter Place Boulevard, Bluffton, SC 29910 (800) 918-8924 Oncology Imaging GUIDELINES Abbreviations for Oncology GUIDELINES ACTH adrenocorticotropic hormone AFP alpha-fetoprotein ALKP alkaline phosphatase AP anteroposterior betaHCG beta human chorionic gonadotropin CA 125 cancer antigen 125 test CA 19-9 cancer antigen 19-9. CA 15-3 cancer antigen 15-3 CA 27-29 cancer antigen 27-29. CBC complete blood count CEA carcinoembryonic antigen CNS central nervous system CR complete response computed tomography CTA DCIS ductal carcinoma in situ angiography DLBCL diffuse large B cell lymphomas DRE digital rectal exam EGD esophagogastroduodenoscopy ENT ear, nose.
6 Throat EOT end of therapy ERCP endoscopic retrograde cholangiopancreatography ESR erythrocyte sedimentation rate EUA exam under anesthesia EUS endoscopic ultrasound FDG fluorodeoxyglucose FNA fine needle aspiration FUO fever of unknown origin GE gastroesophageal GI gastrointestinal GU genitourinary GTR gross total resection HG high grade HIV human immunodeficiency disease hormone refractory prostate Oncology Imaging HRPC hypermet hypermetabolic cancer IFRT Involved field radiation therapy inv invasive LAR low anterior resection LCIS lobular carcinoma in situ LDH lactate dehydrogenase LFT liver function tests LND Lymph node dissection _____. 2021 eviCore healthcare. All Rights Reserved. Page 3 of 309. 400 Buckwalter Place Boulevard, Bluffton, SC 29910 (800)
7 918-8924 Oncology Imaging GUIDELINES mucosa associated lymphoid MALT maint maintenance tissue MEN multiple endocrine neoplasia MG myasthenia gravis MGUS monoclonal gammopathy of unknown significance MIBG I-123 metaiodobenzylguanidine scintigraphy MRA magnetic resonance angiography MRI magnetic resonance imaging MUGA multiple gated acquisition' cardiac nuclear scan MWA microwave ablation NaF Sodium Fluoride NET Neuroendocrine tumor NCCN National Comprehensive Cancer Network NHL non-Hodgkin's lymphoma NPC nasopharyngeal carcinoma NSABP National Surgical Adjuvant Breast and Bowel Project NSAIDS nonsteroidal anti-inflammatory drugs NSCLC non-small cell lung cancer non-seminomatous germ cell NSGCT PA posteroanterior tumor PCI prophylactic cranial irradiation PET positron emission tomography COG Children's Oncology Group PSA prostate specific antigen RFA radiofrequency ablation RPLND retroperitoneal lymph node dissection SqCCa squamous cell carcinoma SCLC small cell lung cancer SIADH syndrome of inappropriate secretion of antidiuretic hormone TCC transitional cell carcinoma TLH total laparoscopic hysterectomy Oncology Imaging TNM tumor node metastasis staging system TSH thyroid-stimulating hormone TURBT trans-urethral resection of bladder tumor VIPoma vasoactive intestinal polypeptide WLE wide local incision WB-MRI whole body MRI.
8 WM Waldenstrom's macroglobulinemia WBXRT Whole brain radiation therapy _____. 2021 eviCore healthcare. All Rights Reserved. Page 4 of 309. 400 Buckwalter Place Boulevard, Bluffton, SC 29910 (800) 918-8924 Oncology Imaging GUIDELINES ONC-1: General GUIDELINES : General GUIDELINES : Key Principles : Phases of Oncology Imaging and General Phase- Related Considerations : Nuclear Medicine (NM) Imaging in Oncology : PET Imaging in Oncology : Unlisted Procedure Codes in Oncology : Predisposition Syndromes Oncology Imaging _____. 2021 eviCore healthcare. All Rights Reserved. Page 5 of 309. 400 Buckwalter Place Boulevard, Bluffton, SC 29910 (800) 918-8924 Oncology Imaging GUIDELINES : General GUIDELINES A recent CLINICAL evaluation (within 60 days) or meaningful contact (telephone call, electronic mail or messaging) should be performed prior to considering advanced imaging, unless the patient is undergoing guideline-supported scheduled off therapy surveillance evaluation or cancer screening.
9 The CLINICAL evaluation may include a relevant history and physical examination, including biopsy, appropriate laboratory studies, and results of non-advanced or advanced imaging modalities. Unless otherwise stated in the disease-specific guideline, a histological confirmation of malignancy (or recurrence) and the stage of disease is required to perform a medical necessity review of the requested imaging. Routine imaging of brain, spine, neck, chest, abdomen, pelvis, bones, or other body areas is not indicated except where explicitly stated in a diagnosis-specific guideline section, or if one of the following applies: Known prior disease involving the requested body area New or worsening symptoms or physical exam findings involving the requested body area (including non-specific findings such as ascites or pleural effusion).
10 New finding on basic imaging study such as plain x-ray or ultrasound New finding on adjacent body area CT/MRI study ( , pleural effusion observed on CT abdomen). Unless otherwise stated in the disease-specific guideline, advanced imaging of asymptomatic individuals is not routinely supported without signs or symptoms of systemic involvement of cancer. Conventional imaging performed prior to diagnosis should not be repeated unless there is a delay of at least 6 weeks since previous imaging and treatment initiation or there are new or significantly worsening CLINICAL signs or symptoms Phase Imaging Timeframe After definitive local therapy of primary tumor Follow surveillance GUIDELINES (surgery or radiation therapy). During adjuvant chemotherapy Follow surveillance GUIDELINES After ablative therapy See disease-specific GUIDELINES During chemotherapy or immunotherapy for Every 2 cycles (generally every 6 to measurable disease 8 weeks).
