Clostridioides（Clostridium）difficile感染症 診療ガイドライン

1 Clostridioides Clostridium difficile Vol. 66 No. 6 645 C. difficile I Clostridioides Clostridium difficile 651II GDH nucleic acid amplification test NAAT 655 CDI 658 CDI NAAT 662 B CDI 667 CDI 671 675 CDI 677 CDI C.

2 difficile 680 CDI 683 Fecal Microbiota Transplantation FMT 685 CDI Antimicrobial stewardship 689 Vol. 66 No. 6 Clostridioides Clostridium difficile 647C. difficile C. difficile CDI GDH C. difficile NAAT NAAT GDH 1 C.

3 difficile 1 GDH NAAT GDH GDH CDI GDH CDI GDH GDH NAAT CDI CDI C. difficile GDH Bristol score 5 NAAT CDI CDI CDIGDH GDH GDH CDI Vol. 66 No. 6 Clostridioides Clostridium difficile 6482 C. difficile 2a.

4 2b GDH NAAT NAAT NAAT 2a GDH NAAT 2b Bristol score 5 GDH CDICDI GDH GDH CDI GDH NAAT CDI CDI CDI Bristol score 5 GDH NAAT GDH NAAT CDI CDI GDH CDI GDH CDICDI CDI ab Vol.

5 66 No. 6 Clostridioides Clostridium difficile 649C. difficile CDI or or or or or or B CDI ( 027 078 244) 3 +/ +/ +/ +/ 2 Vol. 66 No. 6 Clostridioides Clostridium difficile 650I Clostridioides Clostridium difficile Clostridioides Clostridium difficile Clostridioides Clostridium infection CDI C.

6 difficile C. difficile C. difficile B C. difficile C. difficile C. difficile C. difficile C. difficile C. difficile COI COI COI COI Clostridioides Clostrid-ium difficile COI 1 2 3 MSD MSD MSD

7 MSD Meiji Seika Vol. 66 No. 6 651 MSD MSD Meiji Seika MSD MSD Meiji Seika

8 MSD MSD MSD Meiji Seika CDI Vol.

9 66 No. 6 Clostridioides Clostridium difficile 652 / Clostridium difficile Clostridioides Clostridium difficile Clostridioides Clostridium difficile The Japanese Clinical Practice Guidelines for Management of Clostridioides (Clostrid-ium) difficile infections C. difficile C. difficile C. difficile C. difficile C.

10 difficile C. difficile C. difficile C. difficile 1 C. difficile 2 C. difficile 3 C. difficile 4 C. difficile 5 C. difficile 6 C. difficile 7 C. difficile 8 C. difficile Vol. 66 No. 6 Clostridioides Clostridium difficile 653 9 C. difficile 10 C. difficile 1 SR MA 2 Medline SR/MA Medline The Cochrane Library Guideline International Network International Guide-line Library AHRQ National Guideline Clearinghouse 3 PICO 4 2000 2018 6