CURRICULUM VITAE AKHILESH PANDEY, M.D., PH.D. January …

1 CURRICULUM VITAE . AKHILESH PANDEY, , January 28, 2014 . demographic AND personal information . Current Appointments Professor, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine Professor, Biological Chemistry, Johns Hopkins University School of Medicine Professor, Department of Oncology, Johns Hopkins University School of Medicine Professor, Department of Pathology, Johns Hopkins University School of Medicine Professor, Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health personal Data Broadway Research Building, Room 527.

2 733 N. Broadway, Johns Hopkins University Baltimore, MD 21205. Phone: 410-502-6662. Fax: 410-552-7544. E-mail: Education and Training 1984-1988 Armed Forces Medical College, Pune, India - Medicine Internship 1988-1989 Kilpauk Medical College, Madras, India - Medicine 1990-1995 University of Michigan, Ann Arbor, MI - Pathology Postdoctoral Fellow 1995-1996 Laboratory of Vishva Dixit, University of Michigan, Ann Arbor, MI - Molecular Biology Resident 1996-1998 Department of Pathology, Brigham and Women's Hospital, Boston, MA - Clinical Pathology Postdoctoral Fellow 1996-1999 Laboratory of Harvey Lodish, Whitehead Institute/MIT, Cambridge.

3 MA - Molecular Biology Visiting Scientist 1999-2002 Laboratory of Matthias Mann, University of Southern Denmark, Denmark - Mass Spectrometry 1. Professional Experience Instructor Department of Pathology, Harvard Medical School, Boston, MA 1998-2002. Assistant Medical Director Clinical Microbiology Laboratory, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 1998-1999. Assistant Professor McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 2002-2006. Assistant Professor Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 2002-2006.

4 Assistant Professor Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 2004-2006. Assistant Professor Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 2005-2006. Associate Professor McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 2006-2010. Associate Professor Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 2006-2010. Associate Professor Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 2006-2010. RESEARCH ACTIVITIES.

5 Publications i) Peer-reviewed original articles 1. Pandey, A., Tjoelker, and Thompson, (1993). Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V (D) J joining. Journal of Experimental Medicine. 177, 329-337. 2. Pandey, A., Lazar, , Saltiel, and Dixit, (1994). Activation of the Eck Receptor Protein Tyrosine Kinase Stimulates Phosphatidylinositol 3-Kinase Activity. Journal of Biological Chemistry. 269, 30154-30157. 3. Shao, H., Lou, L., Pandey, A., Pasquale, and Dixit, (1994). cDNA cloning and characterization of a ligand for the Cek5 receptor protein-tyrosine kinase.

6 Journal of Biological Chemistry. 269, 26606-26609. 4. Shao, H., Pandey, A., Seldin, M., O'Shea, and Dixit, (1995). Characterization of B61, the ligand for the Eck receptor protein-tyrosine kinase. Journal of Biological Chemistry. 270, 5636-5641. 5. Pandey, A., Duan, H. and Dixit, (1995). Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase. Journal of Biological Chemistry. 270, 19201-19204. 2. 6. Pandey, A., Shao, H., Marks, , Polverini, and Dixit, (1995). Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF- induced angiogenesis. Science.

7 268, 567- 569. 7. Pandey, A., Duan, H., Di Fiore, P. P. and Dixit, (1995). The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10. Journal of Biological Chemistry. 270, 21461-21463. 8. Angrist, M., Wells, D. E., Chakravarti, A. and Pandey, A. (1995). Chromosomal localization of the mouse Src-like adapter protein (SLAP) gene and its putative human homolog SLA. Genomics. 30, 623-625. 9. Pandey, A., Liu, X., Dixon, , Di Fiore, P. P. and Dixit, (1996). Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7.

8 Journal of Biological Chemistry. 271, 10607-10610. 10. Roche, S., Alonso, G., Kazlauskas, A., Dixit, V. M., Courtneidge, S. A. and Pandey, A. (1998). Src-like adaptor protein (Slap) is a negative regulator of mitogenesis. Current Biology. 8, 975-978. 11. Pandey, A., Podtelejnikov, A. V., Blagoev, B., Bustelo, X. R., Mann, M. and Lodish, H. F. (2000). Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2. as a substrate of the epidermal and platelet-derived growth factor receptors. Proceedings of the National Academy of Sciences. 97, 179-184. 12. Sosinowski T., Pandey, A., Dixit, V.

9 M. and Weiss, A. (2000). Src-like adaptor Protein (SLAP) is a negative regulator of T cell receptor signaling. Journal of Experimental Medicine 191, 463-474. 13. Pandey, A., Ozaki, K., Baumann, H., Levin, S. D., Puel, A., Farr, A. G., Ziegler, S. F., Leonard, W. J. and Lodish, H. F. (2000). Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nature Immunology 1, 59-64. 14. Pandey, A., Fernandez, M. M., Steen, H., Blagoev, B., Nielsen, M. M., Mann, M. and Lodish, H. F. (2000). Identification of a novel immunoreceptor tyrosine-based activation motif (ITAM) - containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways.

10 Journal of Biological Chemistry. 275, 38633- 38639. 15. Kratchmarova, I., Sosinowski, T., Weiss, A., Witter, K., Vincenz, C. and Pandey, A. (2001). Characterization of the promoter region and genomic structure of murine and human Src like adapter protein (SLAP) genes. Gene. 262, 267-273. 16. Peri, S. and Pandey, A. (2001). A reassessment of the translation initiation codon in vertebrates. Trends in Genetics. 17, 685-687. 3. 17. Steen, H., K ster, B., Fernandez, M., Pandey, A. and Mann, M. (2001). Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode.