CURRICULUM VITAE Scott Shields Emerson, M.D., Ph.D.

1 CURRICULUM VITAE Scott Shields emerson , , 1. Date: September 19, 2017 2. Biographical Information Professor Emeritus of Biostatistics, University of Washington 7055 54th Avenue NE Seattle, Washington 98115 (206) 459-65213 3. Education University of Virginia, Charlottesville, Virginia, , Physics, 1977 University of Virginia, Charlottesville, Virginia, , Medicine, 1981 University of Virginia, Charlottesville, Virginia, , Computer Science, 1984 University of Washington, Seattle, Washington, , Biostatistics, 1988 4. Licensure: not applicable 5. Professional Positions Postdoctoral Fellow, Department of Biomedical Engineering, University of Virginia, 1981-84 Senior Fellow, Department of Biostatistics, University of Washington, 1984-88 Assistant Professor, Division of Biostatistics, Department of Statistics, University of Florida, 1988-89 Research Assistant Professor, Department of Family and Community Medicine, University of Arizona, 1989-95 Research Associate, Arizona Cancer Center, University of Arizona, 1989-95 Associate Professor, Department of Statistics, University of Arizona, 1992-95 Member, Applied Mathematics, University of Arizona, 1993-95 Associate Professor, Department of Biostatistics.

2 University of Washington, 1995-1999 Associate Member, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1995-2000 Professor, Department of Biostatistics, University of Washington, 1999-2017 Graduate Program Coordinator, Department of Biostatistics University of Washington, 2002-2005, 2014-2017 Professor Emeritus, Department of Biostatistics, University of Washington, 2017-present 6. Honors, Awards, Scholarships Honor Award Scholarship, University of Virginia (1973-77) Echols Scholar, University of Virginia (1973-77) Phi Beta Kappa (1977) NLM Fellowship, Computer Applications to Medicine (1981-84) Scott Shields emerson 2 CURRICULUM VITAE September 19, 2017 NCI Fellowship, Cancer Epidemiology and Biostatistics (1984-88) Donovan J.

3 Thompson Award, University of Washington (1985) WNAR Student Paper Competition, Runner-up (1988) Best Special Contributed Paper, Section on Teaching Statistics in the Health Sciences, American Statistical Association, 1997 Joint Statistical Meetings Outstanding Teaching Award, School of Public Health, 1999 Fellow, American Statistical Association, 2008 Best Contributed Paper, Section on Teaching Statistics in the Health Sciences, American Statistical Association, 2008 Joint Statistical Meetings Best Contributed Paper, Biopharmaceutical Section, American Statistical Association, 2012 Joint Statistical Meetings 7. Professional Activities (outside of UW) Organizer and chair of Joint IMS/WNAR Invited Paper Session: Ethical Issues in Clinical Trials, IMS/WNAR Western Regional Conference, Santa Barbara, California, July 1991.

4 Organizer of ENAR Invited Paper Session: Estimation After Sequential Stopping, ENAR Regional Conference, Cincinnati, Ohio, March 1992. Organizer and chair of Invited Paper Session: Statistical Methods for the Detection of Interactions Between Drugs, 1992 Joint Statistical Meeting, Boston Massachusetts, August, 1992. Invited participant, National Cancer Institute Workshop on Markers of Colon Cell Proliferation, Bethesda, Maryland, October, 1992. Organizer and Chair of Invited Paper Session: Biostatistics Service Courses for Health Sciences Researchers: Where Should We Be in 2007? 1997 Joint Statistical Meeting, Anaheim, California, August 1997. Organizer and Chair of Invited Paper Session: Time-Varying Treatment Effects in Clinical Trials, 2005 Annual Meeting, WNAR, Fairbanks, Alaska, June, 2005.

5 Membership in Professional Organizations: American Statistical Association Program Chair, Section on Epidemiology, 1995-96 Biometric Society Member, Regional Advisory Board, 1993-95 WNAR Representative to Program Committee, 1995 Joint Statistical Meetings President , WNAR, 1999 Society of Clinical Trials Editorial Boards: Associate Editor, American Journal of Epidemiology (1993-97) Statistical Editor, Journal of the National Cancer Institute (1995-2003) Member, Editorial Board, Sequential Analysis (1996-2010) Review of manuscripts submitted for publication to: Journal of the American Statistical Association, Journal of the Royal Statistical Society, Series B, Controlled Clinical Trials, Biometrics, American Journal of Epidemiology, The American Statistician, Statistics in Medicine, Journal of Statistical Planning and Scott Shields emerson 3 CURRICULUM VITAE September 19, 2017 Inference, American Journal of Public Health, Communications in Statistics-Theory and Methods, Biometrical Journal, Journal of the National Cancer Institute, The Statistician, Cancer Research, Lifetime Data Analysis, Clinical Chemistry Appointments, Advisory Boards and Review Committees.

6 Member, ad hoc NCI Technical Review Group for the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial - Study Coordinating and Data Management Center, June 1991. Member, ad hoc NCI Technical Review Groups for the Prostate Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial - Screening Centers, August, 1991. Member, ad hoc NHLBI Special Emphasis Panel for the evaluation of the Data Coordinating Center and Clinical Centers for the Clinical Network for the Treatment of Adult Respiratory Distress Syndrome, April, 1994. Member, NCI Site Visit Committee, University of Pennsylvania Cancer Center core Grant Application. Member, NHLBI Site Visit Committee, Data Coordinating Center for the Clinical Network for the Treatment of Adult Respiratory Distress Syndrome, April 1994.

7 Member, Protocol Review Committee, Adult Respiratory Distress Syndrome Network, NHLBI, 1995-2004. Member, ad hoc NIAMS Technical Review Group for Data Integrity Assessments for NIAMS Clinical Trials, May 1996. Member, Data Safety Monitoring Committee, Multicenter Clinical Trial of E5 in Gram Negative Sepsis, Pfizer, Inc. and Xoma Corporation. Member, Data Safety Monitoring Committee, Multicenter Clinical Trial of rhuMAb HER2 in Breast Cancer, Genentech Corporation. Member, NCI Special Emphasis Panel for PLCO Expansion, July 1997. Member, Data Safety Monitoring Board, Phase II Clinical Trials of rhu Mab CD18, Protodigm. Member, ad hoc NCI Review Group for Breast Cancer Screening Trial, January 1998 Member, ad hoc NCI Review Group for NSABP, April, 1998 Member, Data Safety Monitoring Committee, Multicenter Clinical Trial of BPI in Trauma Patients, Xoma Corporation Member, ad hoc NCI Review Group for PLCO Expansion, June-August, 1998 Member, Data Safety Monitoring Board, Clinical Trial of Apheresis Column in Rheumatoid Arthritis, Otsuka Corporation Member, Data Safety Monitoring Board, Clinical Trials of Histamine in Malignant Melanoma and Acute Myelogenous Leukemia, Maxim Pharmaceuticals Member, Data Safety Monitoring Board, LIMIT Trial, Genentech Corporation Chair, Data Safety Monitoring Board.

8 Clinical Trial of anti-CD11 in Psoriasis, Genentech Member, Data Safety Monitoring Board, Clinical Trial of Efalizumab in Rheumatoid Arthritis, Xoma/Genentech Member, Data Safety Monitoring Board, Clinical Trial of Vaccine in Lung Cancer, Biomira Member, Data Safety Monitoring Board, DFMO and Sulindac in Colon Polyp Prevention, University of California Irvine (NCI sponsored) Chair, Data Safety Monitoring Board, Clinical Trials of Histamine in Malignant Melanoma, Maxim Pharmaceuticals Member, Data Safety Monitoring Board, National Lung Screening Trial, National Cancer Institute Member, FDA Reproductive Drugs Scientific Advisory Panel 2002 - 2006 Scott Shields emerson 4 CURRICULUM VITAE September 19, 2017 Member, Data Safety Monitoring Board, Clinical Trials of rTFPI in Severe Community Acquired Pneumonia, Chiron Member, Internal Data Safety Monitoring Board, Clinical Trial of Aspirin and Biology of the Colon, Fred Hutchinson Cancer Research Center (NIH sponsored)

9 Member, Data Safety Monitoring Board, Clinical Trials of Rituximab in Multiple Sclerosis, Genentech Member, Data Safety Monitoring Board, Clinical Trials of Xolair in Peanut Allergy, Genentech Member, Data Safety Monitoring Board, Clinical Trials of Phenoptin in Phenylketonuria, Biomarin Member, Data Safety Monitoring Board, Clinical Trial in Gastointestinal Stromal Tumors, Agouron Member, Data Safety Monitoring Board, Clinical Trial in Metastatic Breast Cancer, Agouron Member, Data Safety Monitoring Board, Clinical Trial in Renal Cell Cancer, Agouron Member, Data Safety Monitoring Board, Clinical Trial in Cystic Fibrosis, Chiron Member, Data Safety Monitoring Board, Clinical Trial in Hepatitis C Infection, Valeant Member, Data Safety Monitoring Board, International AIDS clinical trials, NIAID, NIH Member, NIH State of the Science Conference Panel on Management of Menopause-Related Symptoms, March 21-23, 2005 Member, Data Safety Monitoring Board, Clinical Trial in Non-Small Cell Lung Cancer, Bayer Member, Data Safety Monitoring Board, Clinical Trial in Biliary Tumors, Helsinn Member, Data Safety Monitoring Board, Clinical Trial in Treatment of Nausea and Vomiting in Chemotherapy, Glaxo Smith-Kline Chair, Data Safety Monitoring Board, Clinical Trial of Massage in Lower Back Pain, Group Health Cooperative (NIH sponsored)

10 Member, Data Safety Monitoring Board, Clinical Trials in Breast Cancer, Pfizer Member, Data Safety Monitoring Board, Clinical Trials in Pancreatic Cancer, Pfizer Member, Clinical Trials Review Committee, NHLBI, 2007-2011. Member, Data Safety Monitoring Board, Clinical Trial in Aspergillosis, Pfizer Chair, Data Safety Monitoring Board, Clinical Trial in Lung Transplantation, APT Member, Data Safety Monitoring Board, Clinical Trial in Chronic Kidney Disease, Novartis Member, National Academy of Sciences Oversight Committee on Missing Data in Clinical Trials Member, FDA Cardiorenal Drugs Scientific Advisory Committee 2011 2014 Ad hoc Member, FDA Gastrointestinal Drugs Scientific Advisory Committee 2013 Chair, NHLBI Special Emphasis Panel, Multicenter Clinical Trials, 2012, 2013, 2014, 2015 Member, DEVOTE clinical trial Steering Committee Ad hoc Member.