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DIニュース - kyoudou-hp.com

1 No596 2018 clostridioides ( clostridium ) difficile ( CDI) CDI (AST) MN CDI CDI AST SSRI SSRI CYP2D6 SSRI 1) SSRI3 2) SSRI clostridioides ( clostridium ) difficile clostridioides ( clostridium ) difficile P1 SSRI P1 2 P3 P3 4 2

Clostridioides(Clostridium)difficile感染症(以下CDI) 診療ガイドライン』が発表さ れました。このガイドラインを参考に当院でのCDI治療指針を抗菌薬適正使用支援チーム (AST)で検討しました。抗C.difficile薬の選択の際に、ご活用下さい。 注意点

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  Clostridium, Difficile, Clostridioides

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Transcription of DIニュース - kyoudou-hp.com

1 1 No596 2018 clostridioides ( clostridium ) difficile ( CDI) CDI (AST) MN CDI CDI AST SSRI SSRI CYP2D6 SSRI 1) SSRI3 2) SSRI clostridioides ( clostridium ) difficile clostridioides ( clostridium ) difficile P1 SSRI P1 2 P3 P3 4 2 2 10mg 5% 34% 95% 36 2 4 5mg 3) SSRI SSRI 4)5)

2 SSRI SSRI 2 4 5mg SSRI 6) 6) 1) 13 14 10 14 24 37 57 95% 1) 2) SSRI . 2009;51(8):769-774. 3) Managing Antidepressant Discontinuation: A Systematic Review. Ann Fam Med. 2019 Ja n;17(1):52-60. 4) Answers to your questions about SSRIs. J Fam Pract. 2010 Jan;59(1):19-25. 5) Step Following Attainment of Remission: Discontinuation of Antidepressant Therapy. Prim Care Companion J Clin Psychiatry. 2001 Aug;3(4):168-174.

3 6) Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018 Apr 7;391(10128):1357-1366. 600mg 300mg 300mg mEq 300mg 1 3 9 3 9 600mg 1 2 1 2 4 32mEq 3 DI L- 1mEq/kg/hr 2 3 70% 30% 600mg 300mg 32mEq mEq 6 1 No 1 1 HMG-CoA 10 10 10

4 30mg 2 2 100 250 20 3 1 3 100 330 40 5 1 / L 2 4 OTC 2 1 1 1 5 100 L 1 1 6 Na 1 2 3 7 75 1 4 / 500 / NSAID 500 / NSAID 1 300 1 500 325 1 3 200 / 500 / 200 / 15mg BZ Cmax Ccr CRE; 33 ( 2 ) - - DS5% 59 /g 5% /g DS3% /g 3% /g OD 4mg/8mg TE 11 4mg/8mg 844 / 10mg / Na 1% 50g/ /g 10mg 5mg 9404


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